True or False? Having pelvic spines is always advantageous to a stickleback. In one sentence, explain your answer. True or False? Dramatic changes in traits, such as the loss of limbs, can occur through mutations affecting a single gene. Provide evidence for your answer. Below is a simplified schematic representation of some of the genetic elements involved in the regulation of Pitx1 gene expression (from HHMI BioInteractive). The large grey rectangle represents the protein-coding region of the Pitx1 The smaller rectangles to the left (b and c) are regulatory switches (networks of regulatory genes); each one allows a specific binding protein to interact with it and turn on the Pitx1 gene in a particular tissue. When expressed, the Pitx1 gene is transcribed and then translated to generate the Pitx1 protein. A deletion at location (a) causes a frameshift mutation, which means that a different mRNA is produced. Recall that mRNA is like the recipe for making a protein. How likely is it that a functional Pitx1 protein would be produced in the jaw? __ In the pelvis? Justify your answers in one or two sentences. If the entire region (b) was deleted, would you see a functional Pitx1 protein in the jaw? _ In the pelvis? ___ Justify your answers in one or two sentences.

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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The Evolution of the Stickleback Fish. Watch the ~15 minute video, Making of the Fittest: Evolution of the Stickleback Fish (https://youtu.be/Pv4Ca-f4W9Q) and the 1 minute video “Stickleback Fish Environment” (https://youtu.be/IRqLy3Oz-oM), both from the Howard Hughes Medical Institute. Answer the questions that follow:
1. True or False? Having pelvic spines is always advantageous to a stickleback. In one sentence, explain your answer.
2. True or False? Dramatic changes in traits, such as the loss of limbs, can occur through mutations affecting a single gene. Provide evidence for your answer.
3. Below is a simplified schematic representation of some of the genetic elements involved in the regulation of Pitx1 gene expression (from HHMI BioInteractive). The large grey rectangle represents the protein-coding region of the Pitx1 The smaller rectangles to the left (b and c) are regulatory switches (networks of regulatory genes); each one allows a specific binding protein to interact with it and turn on the Pitx1 gene in a particular tissue. When expressed, the Pitx1 gene is transcribed and then translated to generate the Pitx1 protein.
  1. A deletion at location (a) causes a frameshift mutation, which means that a different mRNA is produced. Recall that mRNA is like the recipe for making a protein. How likely is it that a functional Pitx1 protein would be produced in the jaw? ____________ In the pelvis? ____________ Justify your answers in one or two sentences.
  2. If the entire region (b) was deleted, would you see a functional Pitx1 protein in the jaw? _____ In the pelvis? _____ Justify your answers in one or two sentences.

Look at Figure 2 of this handout. As a chimpanzee develops from a fetus to an adult, how does its skull change in shape? List at least three ways.
Dnd then what paraphrase the primary hypothesis you will test in this lab. Next, represent this hypothesis as a schematic (concept map), by drawing what you think the ancestral skull looked like and how the shape of the skull evolved in descendent species?

Controls
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expression
in pelvis
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(b)
(c)
(a)
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translation
Pitx1

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