Which of the following compounds spontaneously form electrophiles without bioactivation? A. B. D. E. COOH A. A B. B C. C D. D E. E NO₂ OCH₂ Aristolochic acid C. H.CO. for me & a CI *COOH NH₂ Melphalan Myristicin Diclofenac Benzo[a]pyrene
Reactive Intermediates
In chemistry, reactive intermediates are termed as short-lived, highly reactive atoms with high energy. They rapidly transform into stable particles during a chemical reaction. In specific cases, by means of matrix isolation and at low-temperature reactive intermediates can be isolated.
Hydride Shift
A hydride shift is a rearrangement of a hydrogen atom in a carbocation that occurs to make the molecule more stable. In organic chemistry, rearrangement of the carbocation is very easily seen. This rearrangement can be because of the movement of a carbocation to attain stability in the compound. Such structural reorganization movement is called a shift within molecules. After the shifting of carbocation over the different carbon then they form structural isomers of the previous existing molecule.
Vinylic Carbocation
A carbocation where the positive charge is on the alkene carbon is known as the vinyl carbocation or vinyl cation. The empirical formula for vinyl cation is C2H3+. In the vinyl carbocation, the positive charge is on the carbon atom with the double bond therefore it is sp hybridized. It is known to be a part of various reactions, for example, electrophilic addition of alkynes and solvolysis as well. It plays the role of a reactive intermediate in these reactions.
Cycloheptatrienyl Cation
It is an aromatic carbocation having a general formula, [C7 H7]+. It is also known as the aromatic tropylium ion. Its name is derived from the molecule tropine, which is a seven membered carbon atom ring. Cycloheptatriene or tropylidene was first synthesized from tropine.
Stability of Vinyl Carbocation
Carbocations are positively charged carbon atoms. It is also known as a carbonium ion.
![Which of the following compounds spontaneously form electrophiles without bioactivation?
A.
B.
C.
D.
E.
A. A
B. B
COOH
OCH₂
Aristolochic acid
C. C
D. D
E. E
NO₂
Loc
NH₂
Melphalan
HO
H₂CO
Myristicin
Diclofenac
COOH
Benzo[a]pyrene](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F11be1f3a-cdb0-4acb-99f3-3ad61b2fb7f4%2F5a9ac188-08ac-4f97-b5c3-900dcafbf936%2Fhpwul4r_processed.jpeg&w=3840&q=75)
Step by step
Solved in 3 steps with 1 images
