Which of the following can the results of a QTL tell you? a. Identify all of the causative genes underlying a trait. b. Identify the specific marker locus causes the phenotype you are tracking. c. Identification of regions of the genome that are associated with a trait. d. Identify haplotypes associated with specific traits of interest in other populations.

Which of the following can the results of a QTL tell you? a. Identify all of the causative genes underlying a trait. b. Identify the specific marker locus causes the phenotype you are tracking. c. Identification of regions of the genome that are associated with a trait. d. Identify haplotypes associated with specific traits of interest in other populations.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter18: Genetics Of Behavior

Section: Chapter Questions

Problem 1QP

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To locate genes associated with quantitative traits, geneticists often use QTL mapping (see the introduction to this chapter). To carry out QTL mapping, a first step is crossing two strains that differ in a quantitative trait, such as a strain of corn with high oil content and a strain with low oil content. The F1 progeny of this cross are then interbred or backcrossed to produce an F2 generation. Researchers then look for statistical associations between genetic markers and the value of the quantitative trait (e.g., oil content) in the F2 generation. Why do the geneticists look for statistical associations in the F2 plants? Why not use the F1 progeny?
Which parameters are important to include when designing a GWAS (genome-wide association study) to identify genes involved in Polycystic Kidney disease in individuals of Korean ancestry? Select all that apply. Group of answer choices a. Compare Korean individuals with the disease to unaffected Korean individuals b. Pursue SNPs only in exonic loci for further study c. Pursue SNPS only in genes related to kidney development for further study d. Set strong statistical thresholds to identify SNPs related to the disease state over the general variation observed in populations e. Compare Korean individuals with the disease to every available genome for a stronger statistical power.
A. How does the linkage of traits impact selection decisions in a breeding plan? B. How are molecular markers useful for making selection decisions in the face of linkage drag?
Which of the following statements about mendelian or complex diseases true?. A Genome- wide association studies rely on polymorphic markers that are linkage disequalibrium with alleles that contribute to the traits of interest. B. Genetic methods for studying Mendelian phenotype such as crossing is not useful for mapping quantitive trait loci. C. Mapping of quantitative trait loci does relies on genetic variations that directly contribute to the trait of interest.
Please explain the correct option
Which of the following statements best describe the equation P = G + E + (G X E)?* a. The phenotype is the sum of the genotype and the environment. b. The phenotype of an organism is determined by its genetic traits. c. The phenotype is the total characteristics displayed by an organism that results from the expression of the genes as well as the influence of environmental factors. d. The phenotype is the observable and measurable characteristics of an organism as a result of the interaction of the genes of the organism, environmental factors, and random variation.
What is a quantitative trait locus (QTL)? Does a QTL contain onegene or multiple genes? What technique is commonly used to identify QTLs?
This exercise primarily addresses o MLO 1: Correctly assign and interpret allele symbols according to the conventions of the fruit fly research community. o MLO 2: Correctly assign genotypes and phenotypes to parents and offspring in genetic crosses given a mode of inheritance. Autosomal Recessive Inheritance We learned in the Linkage Mapping lab module the conventions for representing alleles in fruit flies. Recall that we use one to three letters, and the case (upper or lower) is determined by whether the mutant allele is recessive or dominant. Additionally, we add a "+" as a superscript to indicate the wild-type ("normal") allele. For example, if a new mutant phenotype is recessive, we can represent the recessive allele as m. Then the wild-type allele is mt, and m+ > m. Based on the rule of dominance, we can predict phenotypes based on genotypes: mm Wild type Wild type Mutant m+m mm
A geneticist is studying memory recall and is trying to locate specific genes that have varying effects on a given phenotype (physical trait) in the study subjects. These locations of these genes are referred to as: Group of answer choices Genomic spatial identifications Epigenetic regulators Evocative response indicators Quantitative trait loci
Examples of codominance include ABO blood type and coat color in cattle. In short horn cattle coat color pattern is determined by two alleles (CR = red; CW = white) that are both equally expressed. CRCW cattle are roan (red and white patches); therefore, both alleles affect the phenotype equally. The ABO system of blood typing exhibits codominance in humans. There are 3 alleles for the gene that determine ABO blood type (IA and IB are codominant alleles; allelei is recessive to alleles IA and IB). IAIA and I^i are type A; I®I® and IPi are type B; I^IB is type AB; ii is type O Practice Problem 4: 4a. If a man with blood type O marries a woman that is blood type AB, what are the predicted genotypes and phenotypes of their children? 4b. If a man with blood type A (I^i) marries a woman with blood type AB, what are the predicted genotypes and phenotypes of their children?
According to Amar J. S. Klar, is there a such thing as “left handedness”? What is the preferred term? Describe how the genetics works, according to his hypothesis. What are the alleles, and which combinations of alleles make for which type of hand use?
For each of the following genetic topics, indicate whether it focuses on transmission genetics, molecular genetics, or population genetics. a. Analysis of pedigrees to determine the probability of someone inheriting a traitb. Study of people on a small island to determine why a genetic form of asthma is prevalent on the islandc. Effect of nonrandom mating on the distribution of genotypes among a group of animals d. Examination of the nucleotide sequences found at the ends of chromosomese. Mechanisms that ensure a high degree of accuracy in DNA replicationf. Study of how the inheritance of traits encoded by genes on sex chromosomes (sex-linked traits) differs from the inheritance of traits encoded by genes on nonsex chromosomes (autosomal traits)

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	a.	Identify all of the causative genes underlying a trait.
	b.	Identify the specific marker locus causes the phenotype you are tracking.
	c.	Identification of regions of the genome that are associated with a trait.
	d.	Identify haplotypes associated with specific traits of interest in other populations.