Which of the following are TRUE, when describing the Action Potential of a Non- Contractile Cardiac Pacemaker cell? Select ALL that are true. O Resting membrane potential is more polarized than in neurons, because of more Leakage channels for K+. Progressive Na+ channel (the "funny current", iNa) opening, activates a Transient Voltage Sensitive (T-type) Ca++ channel. Together these channels depolarize the membrane and activate Voltage-Sensitive Long-acting (L-Type) Ca++ channel. The resulting depolarization, closes the "funny" current and T-type Ca++ channels. O Action Potential depolarization, resulting from the Voltage-Activated Na+ channel, triggers Voltage-Sensitive Long-acting (L-Type) Ca++ channel. O Membrane depolarization triggers Voltage-Activated K+ channels (Delayed Rectifier) to open. Increasing K+ permeability and repolarizing the membrane. When the membrane polarizes to -60 mv, the Delayed Rectifier closes and a progressive Na+ channel (the "funny current", iNa) opens. The depolarized phase of Action Potential is prolonged (the "plateau phase") by simultaneous opening of the L-Type Ca++ channel and the Voltage-Activated (Delayed Rectifier) K+ channel. V At a membrane polarization of -60 my a progressive Na+ channel (the "funpy
Which of the following are TRUE, when describing the Action Potential of a Non- Contractile Cardiac Pacemaker cell? Select ALL that are true. O Resting membrane potential is more polarized than in neurons, because of more Leakage channels for K+. Progressive Na+ channel (the "funny current", iNa) opening, activates a Transient Voltage Sensitive (T-type) Ca++ channel. Together these channels depolarize the membrane and activate Voltage-Sensitive Long-acting (L-Type) Ca++ channel. The resulting depolarization, closes the "funny" current and T-type Ca++ channels. O Action Potential depolarization, resulting from the Voltage-Activated Na+ channel, triggers Voltage-Sensitive Long-acting (L-Type) Ca++ channel. O Membrane depolarization triggers Voltage-Activated K+ channels (Delayed Rectifier) to open. Increasing K+ permeability and repolarizing the membrane. When the membrane polarizes to -60 mv, the Delayed Rectifier closes and a progressive Na+ channel (the "funny current", iNa) opens. The depolarized phase of Action Potential is prolonged (the "plateau phase") by simultaneous opening of the L-Type Ca++ channel and the Voltage-Activated (Delayed Rectifier) K+ channel. V At a membrane polarization of -60 my a progressive Na+ channel (the "funpy
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter9: Cardiac Physiology
Section: Chapter Questions
Problem 4TAHL
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Question
![Which of the following are TRUE, when describing the Action Potential of a Non-
Contractile Cardiac Pacemaker cell?
Select ALL that are true.
O Resting membrane potential is more polarized than in neurons, because of more
Leakage channels for K+.
Progressive Na+ channel (the "funny current", iNa) opening, activates a Transient
Voltage Sensitive (T-type) Ca++ channel. Together these channels depolarize the
membrane and activate Voltage-Sensitive Long-acting (L-Type) Ca++ channel.
The resulting depolarization, closes the "funny" current and T-type Ca++
channels.
O Action Potential depolarization, resulting from the Voltage-Activated Na+
channel, triggers Voltage-Sensitive Long-acting (L-Type) Ca++ channel.
OMembrane depolarization triggers Voltage-Activated K+ channels (Delayed
Rectifier) to open. Increasing K+ permeability and repolarizing the membrane.
When the membrane polarizes to -60 mv, the Delayed Rectifier closes and a
progressive Na+ channel (the "funny current", iNa) opens.
The depolarized phase of Action Potential is prolonged (the "plateau phase") by
simultaneous opening of the L-Type Ca++ channel and the Voltage-Activated
(Delayed Rectifier) K+ channel.
V At a membrane polarization of -60 my a progressive Na+ channel (the "funpy](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Ff8a66b00-2dc5-4e5a-acfe-63ed4b1c8023%2Fee7bab9b-f448-4b22-94c6-67f31e67e3d7%2F4yank3_processed.jpeg&w=3840&q=75)
Transcribed Image Text:Which of the following are TRUE, when describing the Action Potential of a Non-
Contractile Cardiac Pacemaker cell?
Select ALL that are true.
O Resting membrane potential is more polarized than in neurons, because of more
Leakage channels for K+.
Progressive Na+ channel (the "funny current", iNa) opening, activates a Transient
Voltage Sensitive (T-type) Ca++ channel. Together these channels depolarize the
membrane and activate Voltage-Sensitive Long-acting (L-Type) Ca++ channel.
The resulting depolarization, closes the "funny" current and T-type Ca++
channels.
O Action Potential depolarization, resulting from the Voltage-Activated Na+
channel, triggers Voltage-Sensitive Long-acting (L-Type) Ca++ channel.
OMembrane depolarization triggers Voltage-Activated K+ channels (Delayed
Rectifier) to open. Increasing K+ permeability and repolarizing the membrane.
When the membrane polarizes to -60 mv, the Delayed Rectifier closes and a
progressive Na+ channel (the "funny current", iNa) opens.
The depolarized phase of Action Potential is prolonged (the "plateau phase") by
simultaneous opening of the L-Type Ca++ channel and the Voltage-Activated
(Delayed Rectifier) K+ channel.
V At a membrane polarization of -60 my a progressive Na+ channel (the "funpy
![channel, triggers Voltage-Sensitive Long-acting (L-Type) Ca++ channel.
Membrane depolarization triggers Voltage-Activated K+ channels (Delayed
Rectifier) to open. Increasing K+ permeability and repolarizing the membrane.
When the membrane polarizes to -60 mv, the Delayed Rectifier closes and a
progressive Na+ channel (the "funny current", iNa) opens.
The depolarized phase of Action Potential is prolonged (the "plateau phase") by
simultaneous opening of the L-Type Ca++ channel and the Voltage-Activated
(Delayed Rectifier) K+ channel.
At a membrane polarization of -60 mv, a progressive Na+ channel (the "funny
current", iNa) opens, gradually depolarizing the membrane.
The rapid depolarized phase of Action Potential is produced by opening of the L-
Type Ca++ channel. Repolarization occurs when the L-Type Ca++ channel closes,
and the Voltage-Activated K+ Channel (Delayed Rectifier) opens.
A Graded Potential, arising from a neighboring muscle cell, depolarizes the
membrane to a threshold of -50 mv, triggering Voltage-Activated Na+ channels
to open. Increasing Na+ permeability rapidly depolarizes the membrane.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Ff8a66b00-2dc5-4e5a-acfe-63ed4b1c8023%2Fee7bab9b-f448-4b22-94c6-67f31e67e3d7%2Fzz27nwj_processed.jpeg&w=3840&q=75)
Transcribed Image Text:channel, triggers Voltage-Sensitive Long-acting (L-Type) Ca++ channel.
Membrane depolarization triggers Voltage-Activated K+ channels (Delayed
Rectifier) to open. Increasing K+ permeability and repolarizing the membrane.
When the membrane polarizes to -60 mv, the Delayed Rectifier closes and a
progressive Na+ channel (the "funny current", iNa) opens.
The depolarized phase of Action Potential is prolonged (the "plateau phase") by
simultaneous opening of the L-Type Ca++ channel and the Voltage-Activated
(Delayed Rectifier) K+ channel.
At a membrane polarization of -60 mv, a progressive Na+ channel (the "funny
current", iNa) opens, gradually depolarizing the membrane.
The rapid depolarized phase of Action Potential is produced by opening of the L-
Type Ca++ channel. Repolarization occurs when the L-Type Ca++ channel closes,
and the Voltage-Activated K+ Channel (Delayed Rectifier) opens.
A Graded Potential, arising from a neighboring muscle cell, depolarizes the
membrane to a threshold of -50 mv, triggering Voltage-Activated Na+ channels
to open. Increasing Na+ permeability rapidly depolarizes the membrane.
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