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Which of the following are TRUE, when describing the Action Potential of a Non- Contractile Cardiac Pacemaker cell? Select ALL that are true. O Resting membrane potential is more polarized than in neurons, because of more Leakage channels for K+. Progressive Na+ channel (the "funny current", iNa) opening, activates a Transient Voltage Sensitive (T-type) Ca++ channel. Together these channels depolarize the membrane and activate Voltage-Sensitive Long-acting (L-Type) Ca++ channel. The resulting depolarization, closes the "funny" current and T-type Ca++ channels. O Action Potential depolarization, resulting from the Voltage-Activated Na+ channel, triggers Voltage-Sensitive Long-acting (L-Type) Ca++ channel. O Membrane depolarization triggers Voltage-Activated K+ channels (Delayed Rectifier) to open. Increasing K+ permeability and repolarizing the membrane. When the membrane polarizes to -60 mv, the Delayed Rectifier closes and a progressive Na+ channel (the "funny current", iNa) opens. The depolarized phase of Action Potential is prolonged (the "plateau phase") by simultaneous opening of the L-Type Ca++ channel and the Voltage-Activated (Delayed Rectifier) K+ channel. V At a membrane polarization of -60 my a progressive Na+ channel (the "funpy

Which of the following are TRUE, when describing the Action Potential of a Non- Contractile Cardiac Pacemaker cell? Select ALL that are true. O Resting membrane potential is more polarized than in neurons, because of more Leakage channels for K+. Progressive Na+ channel (the "funny current", iNa) opening, activates a Transient Voltage Sensitive (T-type) Ca++ channel. Together these channels depolarize the membrane and activate Voltage-Sensitive Long-acting (L-Type) Ca++ channel. The resulting depolarization, closes the "funny" current and T-type Ca++ channels. O Action Potential depolarization, resulting from the Voltage-Activated Na+ channel, triggers Voltage-Sensitive Long-acting (L-Type) Ca++ channel. O Membrane depolarization triggers Voltage-Activated K+ channels (Delayed Rectifier) to open. Increasing K+ permeability and repolarizing the membrane. When the membrane polarizes to -60 mv, the Delayed Rectifier closes and a progressive Na+ channel (the "funny current", iNa) opens. The depolarized phase of Action Potential is prolonged (the "plateau phase") by simultaneous opening of the L-Type Ca++ channel and the Voltage-Activated (Delayed Rectifier) K+ channel. V At a membrane polarization of -60 my a progressive Na+ channel (the "funpy

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Which of the following are TRUE, when describing the Action Potential of a Non- Contractile Cardiac Pacemaker cell? Select ALL that are true. O Resting membrane potential is more polarized than in neurons, because of more Leakage channels for K+. Progressive Na+ channel (the "funny current", iNa) opening, activates a Transient Voltage Sensitive (T-type) Ca++ channel. Together these channels depolarize the membrane and activate Voltage-Sensitive Long-acting (L-Type) Ca++ channel. The resulting depolarization, closes the "funny" current and T-type Ca++ channels. O Action Potential depolarization, resulting from the Voltage-Activated Na+ channel, triggers Voltage-Sensitive Long-acting (L-Type) Ca++ channel. OMembrane depolarization triggers Voltage-Activated K+ channels (Delayed Rectifier) to open. Increasing K+ permeability and repolarizing the membrane. When the membrane polarizes to -60 mv, the Delayed Rectifier closes and a progressive Na+ channel (the "funny current", iNa) opens. The depolarized phase of Action Potential is prolonged (the "plateau phase") by simultaneous opening of the L-Type Ca++ channel and the Voltage-Activated (Delayed Rectifier) K+ channel. V At a membrane polarization of -60 my a progressive Na+ channel (the "funpy
Transcribed Image Text:Which of the following are TRUE, when describing the Action Potential of a Non- Contractile Cardiac Pacemaker cell? Select ALL that are true. O Resting membrane potential is more polarized than in neurons, because of more Leakage channels for K+. Progressive Na+ channel (the "funny current", iNa) opening, activates a Transient Voltage Sensitive (T-type) Ca++ channel. Together these channels depolarize the membrane and activate Voltage-Sensitive Long-acting (L-Type) Ca++ channel. The resulting depolarization, closes the "funny" current and T-type Ca++ channels. O Action Potential depolarization, resulting from the Voltage-Activated Na+ channel, triggers Voltage-Sensitive Long-acting (L-Type) Ca++ channel. OMembrane depolarization triggers Voltage-Activated K+ channels (Delayed Rectifier) to open. Increasing K+ permeability and repolarizing the membrane. When the membrane polarizes to -60 mv, the Delayed Rectifier closes and a progressive Na+ channel (the "funny current", iNa) opens. The depolarized phase of Action Potential is prolonged (the "plateau phase") by simultaneous opening of the L-Type Ca++ channel and the Voltage-Activated (Delayed Rectifier) K+ channel. V At a membrane polarization of -60 my a progressive Na+ channel (the "funpy
channel, triggers Voltage-Sensitive Long-acting (L-Type) Ca++ channel. Membrane depolarization triggers Voltage-Activated K+ channels (Delayed Rectifier) to open. Increasing K+ permeability and repolarizing the membrane. When the membrane polarizes to -60 mv, the Delayed Rectifier closes and a progressive Na+ channel (the "funny current", iNa) opens. The depolarized phase of Action Potential is prolonged (the "plateau phase") by simultaneous opening of the L-Type Ca++ channel and the Voltage-Activated (Delayed Rectifier) K+ channel. At a membrane polarization of -60 mv, a progressive Na+ channel (the "funny current", iNa) opens, gradually depolarizing the membrane. The rapid depolarized phase of Action Potential is produced by opening of the L- Type Ca++ channel. Repolarization occurs when the L-Type Ca++ channel closes, and the Voltage-Activated K+ Channel (Delayed Rectifier) opens. A Graded Potential, arising from a neighboring muscle cell, depolarizes the membrane to a threshold of -50 mv, triggering Voltage-Activated Na+ channels to open. Increasing Na+ permeability rapidly depolarizes the membrane.
Transcribed Image Text:channel, triggers Voltage-Sensitive Long-acting (L-Type) Ca++ channel. Membrane depolarization triggers Voltage-Activated K+ channels (Delayed Rectifier) to open. Increasing K+ permeability and repolarizing the membrane. When the membrane polarizes to -60 mv, the Delayed Rectifier closes and a progressive Na+ channel (the "funny current", iNa) opens. The depolarized phase of Action Potential is prolonged (the "plateau phase") by simultaneous opening of the L-Type Ca++ channel and the Voltage-Activated (Delayed Rectifier) K+ channel. At a membrane polarization of -60 mv, a progressive Na+ channel (the "funny current", iNa) opens, gradually depolarizing the membrane. The rapid depolarized phase of Action Potential is produced by opening of the L- Type Ca++ channel. Repolarization occurs when the L-Type Ca++ channel closes, and the Voltage-Activated K+ Channel (Delayed Rectifier) opens. A Graded Potential, arising from a neighboring muscle cell, depolarizes the membrane to a threshold of -50 mv, triggering Voltage-Activated Na+ channels to open. Increasing Na+ permeability rapidly depolarizes the membrane.
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