**Possible Reasons for a Postsynaptic Neuron's Failure to Trigger an Action Potential**In the study of neuroscience, several factors can explain why a postsynaptic neuron fails to trigger an action potential. Understanding these factors is crucial for comprehending how neurons communicate and how this communication can sometimes fail. Below are the likely explanations:1. **Neutralization of EPSPs** - The excitatory postsynaptic potentials (EPSPs) are neutralized by neurotransmitters. This means the neurotransmitter might inhibit the needed increase in membrane potential, thus preventing the neuron from reaching the threshold to trigger an action potential.2. **Insufficient Summation of IPSPs and EPSPs** - The summation of inhibitory postsynaptic potentials (IPSPs) and EPSPs is insufficient to depolarize the cell to the threshold level required for an action potential to occur. This suggests a balance or imbalance between the inhibitory and excitatory signals that the neuron receives, affecting its ability to fire.3. **Proximity of Synapses to the Axon Hillock** - The synapses generating the EPSPs are too close to the axon hillock. This can lead to ineffective spatial summation where the proximity to the axon hillock means the potentials decay before reaching a threshold voltage.4. **Distance of Synapses from the Axon Hillock** - The synapses generating the EPSPs are too far from the axon hillock. Here, the degradation of the EPSP due to the long distance it must travel could prevent the membrane potential from reaching the necessary threshold for action potential initiation.Understanding these factors provides insight into the complexity of neuronal communication and the various elements that can influence the generation of an action potential.

The postsynaptic element is often the soma or dendrite of a postsynaptic neuron. The other side of…

Which of the following are the likely explanations for the failure of a postsynaptic neuron to trigger an action potential? Select all that apply. The EPSPs are neutralized by the neurotransmitter The summation of IPSPs and EPSPS is insufficient to depolarize the cell to threshold The synapses generating the EPSPs are too close to the axon hillock The synapses generating the EPSPs are too far from the axon hillock 0000

Which of the following are the likely explanations for the failure of a postsynaptic neuron to trigger an action potential? Select all that apply. The EPSPs are neutralized by the neurotransmitter The summation of IPSPs and EPSPS is insufficient to depolarize the cell to threshold The synapses generating the EPSPs are too close to the axon hillock The synapses generating the EPSPs are too far from the axon hillock 0000

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter4: Principles Of Neural And Hormonal Communication

Section: Chapter Questions

Problem 4TAHL: Assume presynaptic excitatory neuron A terminates on a postsynaptic cell near the axon hillock and...

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