**Title: Retrosynthetic Analysis Question in Organic Chemistry****Introduction:**When conducting retrosynthetic analysis for the target synthesis shown, determining the appropriate initial question is essential for guiding the synthesis strategy.**Chemical Reaction Diagram:**The diagram depicts the transformation of a terminal alkyne into a vinyl bromide. The alkyne has a triple bond between two carbon atoms, and the vinyl bromide product has a double bond adjacent to a bromine atom.**Multiple Choice Question:**When performing a retrosynthetic analysis for the desired synthesis below, what is the best question to ask *first*?- ○ What conditions should I use to brominate an alkane?- ○ From what functional group can a vinyl bromide be made?- ○ How do you convert an alkyl halide into an alkene?- ○ How do you convert a vinyl halide into an alkyne?**Analysis:**Choosing the right initial question helps establish the synthesis path, focusing on the conversion of functional groups and exploring the reactions needed to achieve the target molecule.

In the given synthesis - Reactant is alkyne and it is converted into vinyl bromide. For converting this reactant best question should be - From which functional group vinyl halide can be made? So option b is correct. In option 1 , alkane is not brominated here. In option 3, alkyl halide is not converted into alkene here. In option 4 , vinyl halide is not converting into alkyne ,just its reverse reaction is occurring. So these three options are wrong.Option 2 is correct.

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When performing a retrosynthetic analysis for the desired synthesis below, what is the best question to ask first? Br What conditions should I use to brominate an alkane? From what functional group can a vinyl bromide be made? How do you convert an alkyl halide into an alkene? How do you convert a vinyl halide into an alkyne?

When performing a retrosynthetic analysis for the desired synthesis below, what is the best question to ask first? Br What conditions should I use to brominate an alkane? From what functional group can a vinyl bromide be made? How do you convert an alkyl halide into an alkene? How do you convert a vinyl halide into an alkyne?

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Designing a Synthesis

Organic synthesis is a branch of chemical synthesis that involves the planned construction of organic compounds/molecules from smaller units that possess functional groups. Friedrich Wöhler was the first scientist who designed the synthesis of an organic compound, urea from inorganic starting materials silver cyanate with ammonium chloride via a simple, one-step synthesis.

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