What steps would a cell take to oxidize into carbon dioxide the four carbons of malate? List the enzyme of each reaction that leads to the oxidation of each carbons to CO2.

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter17: Metabolism: An Overview
Section: Chapter Questions
Problem 12P: How Do Vitamin-Derived Coenzymes Aid Metabolism? What chemical functionality is provided to enzyme...
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What steps would a cell take to oxidize into carbon dioxide the four carbons of malate? List the enzyme of each reaction that leads to the oxidation of each carbons to CO2. 

My professor said something about gluconeogenesis but I still not can understand their relationship. Is it because malate can oxidize to oxaloacetate thought enzyme malate dehydrogenase and then this oxaloacetate can join the gluconeogenesis pathway to product phosphoenolpyruvate, and then this PEP go to glycolysis pathway produce pyruvate?

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So for route 1, when OAA decarboxylated to PEP. Are the can immediately converted to pyruvate by enzyme pyruvate kinase or they go completely the gluconeogenesis to product the glucose, and the that glucose break down to pyruvate through glycolysis?

 

 

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