? What smeant by clonal selection? Development Hematopoietic stem cell Immature B cells: As these develop, a functionally limitless assortment of B-cell receptors is randomly generated. Antigen X Naive B cells: Each cell is programmed to recognize a specific epitope on an antigen; B-cell receptors guide that recognition. B cell X recognizing antigen X B cell W B cell Y B cell Z Selected B cell receives confirmation from a specific TH cell that a response is warranted (not shown here; process is illustrated in figure 15.11) Activation Activated B cells: These cells can proliferate because their B-cell receptors are bound to antigen X and the cells have received required cells. signals from TH Proliferation and differentiation Plasma cells (effector B cells): These descendants of activated B cells secrete large quantities of antibody molecules that bind to antigen X. Memory B cells: These long-lived descendants of activated B cells recognize antigen X when it is encountered again. Effector action Antibodies: These neutralize the invader and tag it for destruction.
? What smeant by clonal selection? Development Hematopoietic stem cell Immature B cells: As these develop, a functionally limitless assortment of B-cell receptors is randomly generated. Antigen X Naive B cells: Each cell is programmed to recognize a specific epitope on an antigen; B-cell receptors guide that recognition. B cell X recognizing antigen X B cell W B cell Y B cell Z Selected B cell receives confirmation from a specific TH cell that a response is warranted (not shown here; process is illustrated in figure 15.11) Activation Activated B cells: These cells can proliferate because their B-cell receptors are bound to antigen X and the cells have received required cells. signals from TH Proliferation and differentiation Plasma cells (effector B cells): These descendants of activated B cells secrete large quantities of antibody molecules that bind to antigen X. Memory B cells: These long-lived descendants of activated B cells recognize antigen X when it is encountered again. Effector action Antibodies: These neutralize the invader and tag it for destruction.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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What is meant by clonal selection?
Transcribed Image Text:? What
smeant by clonal selection?
Development
Hematopoietic stem cell
Immature B cells: As
these develop, a
functionally limitless
assortment of B-cell
receptors is randomly
generated.
Antigen X
Naive B cells: Each
cell is programmed to
recognize a specific
epitope on an antigen;
B-cell receptors guide
that recognition.
B cell X
recognizing antigen X
B cell W
B cell Y
B cell Z
Selected B cell receives confirmation from a specific
TH cell that a response is warranted (not shown
here; process is illustrated in figure 15.11)
Activation
Activated B cells:
These cells can
proliferate because
their B-cell receptors
are bound to antigen X
and the cells have
received required
cells.
signals from TH
Proliferation and
differentiation
Plasma cells
(effector B cells):
These descendants of
activated B cells
secrete large quantities
of antibody molecules
that bind to antigen X.
Memory B cells:
These long-lived
descendants of
activated B cells
recognize antigen X
when it is encountered
again.
Effector action
Antibodies:
These neutralize the
invader and tag it for
destruction.
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