What is the Reverse transcriptase (RT) inhibitors? Explain with an example and describe its structure. What is the oral absorption of a drug? Describe completely.

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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Short examination of Advanced Medicinal Chemistry course
1. What is the Reverse transcriptase (RT) inhibitors? Explain with an example and describe its structure.
2. What is the oral absorption of a drug? Describe completely.
3. What is the following structure about? Describe with details.
PEPTIDE(1)
PEPTIDE(1)
NH
NH
NH
HN
CO----
---HN
0
SERINE PROTEASE
0=
YX
MIX
HN
Co,H
O
CO₂H
PENICILLINS
CO₂H
---HN
SERINE PROTEASE
4. Mention to the five Protease inhibitors containing sulfonamide functional moiety.
5. Explian the H2 Receptor Antagonists.
6. Write the synthesis pathway for the Zantac.
NHMe
none
NO₂
ranitidine
(Zantac)
7. Explain the cyclin-dependent kinases, completely.
8. Describe DNA ALKYLATING AGENTS.
R
Transcribed Image Text:Short examination of Advanced Medicinal Chemistry course 1. What is the Reverse transcriptase (RT) inhibitors? Explain with an example and describe its structure. 2. What is the oral absorption of a drug? Describe completely. 3. What is the following structure about? Describe with details. PEPTIDE(1) PEPTIDE(1) NH NH NH HN CO---- ---HN 0 SERINE PROTEASE 0= YX MIX HN Co,H O CO₂H PENICILLINS CO₂H ---HN SERINE PROTEASE 4. Mention to the five Protease inhibitors containing sulfonamide functional moiety. 5. Explian the H2 Receptor Antagonists. 6. Write the synthesis pathway for the Zantac. NHMe none NO₂ ranitidine (Zantac) 7. Explain the cyclin-dependent kinases, completely. 8. Describe DNA ALKYLATING AGENTS. R
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