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Answer both questions about the following important ligands in cell signaling.
- Estrogen
- Epinephrine
- EGF
- Insulin
- Cortisol
Step by step
Solved in 2 steps
- A) Please explain what a G protein coupled receptor is. Please explain how G protein interacts with this receptor. B) Please explain the kind of reactions that follow binding a specific ligand to a G protein coupled receptor. What do these reactions do in the cell? C) How do these reactions work in the cell. What is the function of these reactions in the cell? How do the reactions proceed?What are G-protein coupled receptors? How does ligand binding activates GPCR (include in your answer, the types of G-proteins and the second messenger systems involved in the translation of a pharmacological response when a ligand binds to GPCR)?What does the affinity of a binding site for a ligand determine?
- What role does phosphorylation of tyrosine residues play in the action of receptor proteins?An extracellular signaling molecule binds to cell surface receptor. This cell surface receptor changes shape and activates a trimeric G-protein. What kind of receptor is this? a) Ion-channel coupled receptor b) Receptor Tyrosine Kinase c) G-Protein coupled receptor d) All of the other answers are correct e) Enzyme-coupled receptorWhat are g-coupled protein receptors? Explain the role they play in cell physiology.
- Describe the process and results of receptor-ligand binding.What are the features of Receptor?Signaling by tyrosine kinase receptors is generally associated with all of the following except: OA) receptor dimerization B) growth factor responses C) heterotrimeric G proteins OD) cross phosphorylation E) generating protein binding sites due to phosphorylation