What is the effect of treatment of CER cells with chloroquine? Explain.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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The early steps of rabiesvirus (CVS) infection in vitro were studied in chicken embryo
cells (CER) cells. The infection was monitored by looking for specific viral inclusions using anti-
rabies fluorescein isothiocynanate at 24 hours after addition of virus. Cells were incubated for
various lengths of time after virus attachment with ammonium chloride and chloroquine. The
results are show in Figure 2.
100
75
s0
I 3 5 7
Time (h)
24
(m) 20 mM NH,CI
(0) 0.1 mM chloroquine
Figure 2
What is the effect of treatment of CER cells with chloroquine? Explain.
Fluorescence inhibition (%)
Transcribed Image Text:The early steps of rabiesvirus (CVS) infection in vitro were studied in chicken embryo cells (CER) cells. The infection was monitored by looking for specific viral inclusions using anti- rabies fluorescein isothiocynanate at 24 hours after addition of virus. Cells were incubated for various lengths of time after virus attachment with ammonium chloride and chloroquine. The results are show in Figure 2. 100 75 s0 I 3 5 7 Time (h) 24 (m) 20 mM NH,CI (0) 0.1 mM chloroquine Figure 2 What is the effect of treatment of CER cells with chloroquine? Explain. Fluorescence inhibition (%)
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