Wasting is one of the characteristics of HIV / Aids, caused by increased metabolic activity. Untreated patients quickly lose up to 10% of their body weight, with loss of muscle mass contributing most. What happens to the amino group of amino acids that are broken down in the muscles? Fully explain the process of amino acid degradation in the muscle up to urea production in the liver.

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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Wasting is one of the characteristics of HIV / Aids, caused by increased metabolic activity. Untreated patients quickly lose up to 10% of their body weight, with loss of muscle mass contributing most.
What happens to the amino group of amino acids that are broken down in the muscles? Fully explain the process of amino acid degradation in the muscle up to urea production in the liver.
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Amino acid degradation is a complex web of reactions. It is necessary because, unlike fats and carbohydrates, excess amino acids can not be stored. The majority of amino amino acid degradation occurs in the liver and skeletal muscles. Amino acid degradation is the major process responsible for loss of body weight and muscle mass in AIDS, a process called Wasting.

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