V Figure 5.14 the 20 amino acida of proteine. The emina ecids eegrouged here eeraing to the oree therade cheira (Rgrouge end shownin their oelng larie form at gH 7.2, the pH wthin al. e thre-istiar erd oreetar betiora tor the amino eceein pererthan. All of the emino da uaad in proteire eeLerentiorers igue Nonpolar side chatns, hydrophobe saec Ik goupl H--C- y---o HNI---o H-(-C-o Glyine Alrine bolucine le er valne Laucine H--C-o Ht--C- Methknine et or M rterylalr the or ypoplue iper wi Pudne Polar side chuims hydrophie Seoew aaronto ad SH HN--C-o HN--C-0 Ht--C- HO Serine Ser or theer tihr or 10 ynite cutanne inor o Apge tlectrkally changed sde chaina; hydraphilk Basic fpostivily changod Acidic nogatiwly chargpd H---o H--- Hy--- --- HO Aurte ad Cutani ad lyane Hdne dor 0 Ngnine

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Considering the chemical characteristics of the amino acids valine and glutamic acid (see Figure 5.14), propose a possible explanation for the dramatic effect on protein function that occurs when valine is substituted for glutamic acid.

V Figure 5.14 the 20 amino acida of proteine. The emina ecids eegrouged here eeraing to the
oree therade cheira (Rgrouge end shownin their oelng larie form at gH 7.2, the pH wthin
al. e thre-istiar erd oreetar betiora tor the amino eceein pererthan. All of the emino
da uaad in proteire eeLerentiorers igue
Nonpolar side chatns, hydrophobe
saec
Ik goupl
H--C-
y---o
HNI---o
H-(-C-o
Glyine
Alrine
bolucine
le er
valne
Laucine
H--C-o
Ht--C-
Methknine
et or M
rterylalr
the or
ypoplue
iper wi
Pudne
Polar side chuims hydrophie
Seoew
aaronto ad
SH
HN--C-o
HN--C-0
Ht--C-
HO
Serine
Ser or
theer
tihr or 10
ynite
cutanne
inor o
Apge
tlectrkally changed sde chaina; hydraphilk
Basic fpostivily changod
Acidic nogatiwly chargpd
H---o
H---
Hy---
---
HO
Aurte ad
Cutani ad
lyane
Hdne
dor 0
Ngnine
Transcribed Image Text:V Figure 5.14 the 20 amino acida of proteine. The emina ecids eegrouged here eeraing to the oree therade cheira (Rgrouge end shownin their oelng larie form at gH 7.2, the pH wthin al. e thre-istiar erd oreetar betiora tor the amino eceein pererthan. All of the emino da uaad in proteire eeLerentiorers igue Nonpolar side chatns, hydrophobe saec Ik goupl H--C- y---o HNI---o H-(-C-o Glyine Alrine bolucine le er valne Laucine H--C-o Ht--C- Methknine et or M rterylalr the or ypoplue iper wi Pudne Polar side chuims hydrophie Seoew aaronto ad SH HN--C-o HN--C-0 Ht--C- HO Serine Ser or theer tihr or 10 ynite cutanne inor o Apge tlectrkally changed sde chaina; hydraphilk Basic fpostivily changod Acidic nogatiwly chargpd H---o H--- Hy--- --- HO Aurte ad Cutani ad lyane Hdne dor 0 Ngnine
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