Use the following figure to answer the question. юдо TO The pedigree in the figure shows the transmission of a trait in a particular family. The filled in males and females express a disorder in the cells mitochondrion. What pattern in the pedigree makes sense in terms of this disorder? O the disorder must be autosomal dominant the disorder must be sex-linked recessive only females pass on the disorder to offspring males are more likely to receive the gene
Use the following figure to answer the question. юдо TO The pedigree in the figure shows the transmission of a trait in a particular family. The filled in males and females express a disorder in the cells mitochondrion. What pattern in the pedigree makes sense in terms of this disorder? O the disorder must be autosomal dominant the disorder must be sex-linked recessive only females pass on the disorder to offspring males are more likely to receive the gene
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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
Transcribed Image Text:### Understanding Pedigree Analysis in Genetic Disorders
**Pedigree Diagram Explanation:**
The pedigree chart depicted above shows the transmission of a genetic trait within a family across multiple generations. In the chart:
- Squares represent males.
- Circles represent females.
- Filled symbols (either squares or circles) indicate individuals who exhibit a particular genetic disorder.
- Unfilled symbols indicate individuals who do not exhibit the disorder.
The connections between symbols demonstrate familial relationships:
- A horizontal line connecting a square and a circle represents a mating between a male and a female.
- Vertical lines extending from this mating line represent their offspring.
- Siblings are arranged horizontally and connected to their parents by a vertical line descending from the mating line.
**Pedigree Chart Analysis:**
The question associated with this chart is: "What pattern in the pedigree makes sense in terms of this disorder?"
The provided options are:
1. The disorder must be autosomal dominant.
2. The disorder must be sex-linked recessive.
3. Only females pass on the disorder to offspring.
4. Males are more likely to receive the gene.
The correct option chosen is: **Males are more likely to receive the gene**.
**Interpreting the Correct Answer:**
1. **Autosomal Dominant:**
- Affected individuals would appear in every generation, and both males and females would be equally likely to inherit and exhibit the disorder.
2. **Sex-Linked Recessive:**
- This type of inheritance is often seen more frequently in males since males only have one X chromosome. However, carrier females would commonly express traits in their male offspring but not necessarily in all females.
3. **Maternal Inheritance (only females pass it on):**
- Traits due to mutations in mitochondrial DNA would be passed from mothers to all offspring, but males do not pass it on. This does suggest mitochondrial inheritance.
4. **Male Predominance:**
- If males are more affected than females, this would support a sex-linked recessive pattern since males (with only one X chromosome) are more frequently affected by such disorders.
Given the patterns observed, especially with more males being affected, the disorder likely follows a sex-linked recessive inheritance pattern. This implies that males are more likely to receive the gene due to the nature of X-linked inheritance.
### Educational Takeaways:
- **Autosomal Dominant Disorders:** Appear in each generation and affect males and females equally.
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