Use the following figure to answer the question. юдо TO The pedigree in the figure shows the transmission of a trait in a particular family. The filled in males and females express a disorder in the cells mitochondrion. What pattern in the pedigree makes sense in terms of this disorder? O the disorder must be autosomal dominant the disorder must be sex-linked recessive only females pass on the disorder to offspring males are more likely to receive the gene

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
Topic Video
Question
### Understanding Pedigree Analysis in Genetic Disorders

**Pedigree Diagram Explanation:**

The pedigree chart depicted above shows the transmission of a genetic trait within a family across multiple generations. In the chart:

- Squares represent males.
- Circles represent females.
- Filled symbols (either squares or circles) indicate individuals who exhibit a particular genetic disorder.
- Unfilled symbols indicate individuals who do not exhibit the disorder.

The connections between symbols demonstrate familial relationships:
- A horizontal line connecting a square and a circle represents a mating between a male and a female.
- Vertical lines extending from this mating line represent their offspring.
- Siblings are arranged horizontally and connected to their parents by a vertical line descending from the mating line.

**Pedigree Chart Analysis:**

The question associated with this chart is: "What pattern in the pedigree makes sense in terms of this disorder?" 

The provided options are:
1. The disorder must be autosomal dominant.
2. The disorder must be sex-linked recessive.
3. Only females pass on the disorder to offspring.
4. Males are more likely to receive the gene.

The correct option chosen is: **Males are more likely to receive the gene**.

**Interpreting the Correct Answer:**

1. **Autosomal Dominant:** 
   - Affected individuals would appear in every generation, and both males and females would be equally likely to inherit and exhibit the disorder.

2. **Sex-Linked Recessive:**
   - This type of inheritance is often seen more frequently in males since males only have one X chromosome. However, carrier females would commonly express traits in their male offspring but not necessarily in all females.

3. **Maternal Inheritance (only females pass it on):**
   - Traits due to mutations in mitochondrial DNA would be passed from mothers to all offspring, but males do not pass it on. This does suggest mitochondrial inheritance.

4. **Male Predominance:**
   - If males are more affected than females, this would support a sex-linked recessive pattern since males (with only one X chromosome) are more frequently affected by such disorders. 

Given the patterns observed, especially with more males being affected, the disorder likely follows a sex-linked recessive inheritance pattern. This implies that males are more likely to receive the gene due to the nature of X-linked inheritance.

### Educational Takeaways:
- **Autosomal Dominant Disorders:** Appear in each generation and affect males and females equally.
Transcribed Image Text:### Understanding Pedigree Analysis in Genetic Disorders **Pedigree Diagram Explanation:** The pedigree chart depicted above shows the transmission of a genetic trait within a family across multiple generations. In the chart: - Squares represent males. - Circles represent females. - Filled symbols (either squares or circles) indicate individuals who exhibit a particular genetic disorder. - Unfilled symbols indicate individuals who do not exhibit the disorder. The connections between symbols demonstrate familial relationships: - A horizontal line connecting a square and a circle represents a mating between a male and a female. - Vertical lines extending from this mating line represent their offspring. - Siblings are arranged horizontally and connected to their parents by a vertical line descending from the mating line. **Pedigree Chart Analysis:** The question associated with this chart is: "What pattern in the pedigree makes sense in terms of this disorder?" The provided options are: 1. The disorder must be autosomal dominant. 2. The disorder must be sex-linked recessive. 3. Only females pass on the disorder to offspring. 4. Males are more likely to receive the gene. The correct option chosen is: **Males are more likely to receive the gene**. **Interpreting the Correct Answer:** 1. **Autosomal Dominant:** - Affected individuals would appear in every generation, and both males and females would be equally likely to inherit and exhibit the disorder. 2. **Sex-Linked Recessive:** - This type of inheritance is often seen more frequently in males since males only have one X chromosome. However, carrier females would commonly express traits in their male offspring but not necessarily in all females. 3. **Maternal Inheritance (only females pass it on):** - Traits due to mutations in mitochondrial DNA would be passed from mothers to all offspring, but males do not pass it on. This does suggest mitochondrial inheritance. 4. **Male Predominance:** - If males are more affected than females, this would support a sex-linked recessive pattern since males (with only one X chromosome) are more frequently affected by such disorders. Given the patterns observed, especially with more males being affected, the disorder likely follows a sex-linked recessive inheritance pattern. This implies that males are more likely to receive the gene due to the nature of X-linked inheritance. ### Educational Takeaways: - **Autosomal Dominant Disorders:** Appear in each generation and affect males and females equally.
Expert Solution
steps

Step by step

Solved in 2 steps

Blurred answer
Knowledge Booster
Mitochondrial mutations
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education