Two-year-old Janice Tumminello survived an episode of Haemophilus influenzae septicemia at 4 months by intravenous antibiotic therapy. Her immunizations are up to date. Three days ago her adoptive parents became concerned when she became lethargic, had several bouts of vomiting, and developed a fever, and they took her to the emergency room. She had a rapid pulse and low blood pressure, her peripheral areas were cold, and purpura began to develop on her fingers and toes. Blood cultures tested positive for Streptococcus pneumoniae. Aggressive antibiotic treatment and fluid-replacement therapy were successful in preventing further dissemination of the bacteremia. However, amputation of three digits on the left hand and debridement of her toes on both feet was required. A diagnosis of overwhelming severe pneumococcal sepsis was made. DNA analysis showed that Janice had a deleterious mutation in a gene encoding _____, which is associated with congenital asplenia. a. an immunoglobulin b. a defensin c. a ribosomal protein d. a complement protein e. a T-cell receptor.
Two-year-old Janice Tumminello survived an episode of Haemophilus influenzae septicemia at 4 months by intravenous antibiotic therapy. Her immunizations are up to date. Three days ago her adoptive parents became concerned when she became lethargic, had several bouts of vomiting, and developed a fever, and they took her to the emergency room. She had a rapid pulse and low blood pressure, her peripheral areas were cold, and purpura began to develop on her fingers and toes. Blood cultures tested positive for Streptococcus pneumoniae. Aggressive antibiotic treatment and fluid-replacement therapy were successful in preventing further dissemination of the bacteremia. However, amputation of three digits on the left hand and debridement of her toes on both feet was required. A diagnosis of overwhelming severe pneumococcal sepsis was made. DNA analysis showed that Janice had a deleterious mutation in a gene encoding _____, which is associated with congenital asplenia. a. an immunoglobulin b. a defensin c. a ribosomal protein d. a complement protein e. a T-cell receptor.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
Related questions
Question
| Two-year-old Janice Tumminello survived an episode of Haemophilus influenzae septicemia at 4 months by intravenous antibiotic therapy. Her immunizations are up to date. Three days ago her adoptive parents became concerned when she became lethargic, had several bouts of vomiting, and developed a fever, and they took her to the emergency room. She had a rapid pulse and low blood pressure, her peripheral areas were cold, and purpura began to develop on her fingers and toes. Blood cultures tested positive for Streptococcus pneumoniae. Aggressive antibiotic treatment and fluid-replacement therapy were successful in preventing further dissemination of the bacteremia. However, amputation of three digits on the left hand and debridement of her toes on both feet was required. A diagnosis of overwhelming severe pneumococcal sepsis was made. DNA analysis showed that Janice had a deleterious mutation in a gene encoding _____, which is associated with congenital asplenia. |
| a. an immunoglobulin |
| b. a defensin |
| c. a ribosomal protein |
| d. a complement protein |
| e. a T-cell receptor. |
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution!
Trending now
This is a popular solution!
Step by step
Solved in 3 steps
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education