2.2 The importance of pseudouridine in the making of RNA vaccines is: A) it reduces the tendency for the immune system to activate B-cells, which then destroy the vaccine before it can be taken up by cells. B) it reduces the interferon based response to foreign RNA, which would suppress translation and prevent the MRNA from being expressed as protein. C) Unlike uridine, it can base pair with either adenosine or thymidine D) because it is more negatively charged than uridine, it binds more stably to cationic lipids and can be packaged more efficiently.
2.2 The importance of pseudouridine in the making of RNA vaccines is: A) it reduces the tendency for the immune system to activate B-cells, which then destroy the vaccine before it can be taken up by cells. B) it reduces the interferon based response to foreign RNA, which would suppress translation and prevent the MRNA from being expressed as protein. C) Unlike uridine, it can base pair with either adenosine or thymidine D) because it is more negatively charged than uridine, it binds more stably to cationic lipids and can be packaged more efficiently.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:2.2 The importance of pseudouridine in the making of RNA vaccines is:
A) it reduces the tendency for the immune system to activate B-cells, which then destroy the
vaccine before it can be taken up by cells.
B) it reduces the interferon based response to foreign RNA, which would suppress translation
and prevent the MRNA from being expressed as protein.
C) Unlike uridine, it can base pair with either adenosine or thymidine
D) because it is more negatively charged than uridine, it binds more stably to cationic lipids
and can be packaged more efficiently.
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