Trypsin is a digestive enzyme that cleaves proteins into smaller peptide fragments. It does so by hydrolyzing the amide bond (peptide bond) on the C-terminal side of positively-charged amino acids. Draw the three hydrolysis products that result when trypsin reacts with the pentapeptide KINKY at pH 7.4. Recall: the hydrolysis of amide bonds involves the addition of water. Where does the water show up in the products of the reaction?
Neutral Amino Acids
Amino acids which do not have any charge on them are neutral amino acids.
Globular Protein
The globular proteins refer to the shape of protein specifically spherical in nature apart from spherical form fibrous, disordered and membrane-bound proteins exist. These globular proteins are miscible in water and form a colloidal solution rather than other types which might not exhibit solubility. Many classes of the fold are found in globular proteins, which render them a sphere shape. Globular fold containing proteins usually are referred to by the term globin.
Dimer
Dimers are basic organic compounds, which are derivates of oligomers. It is formed by the combination of two monomers which could potentially be strong or weak and in most cases covalent or intermolecular in nature. Identical monomers are called homodimer, the non-identical dimers are called heterodimer. The method by which dimers are formed is known as “dimerization”.
Dipeptide
A dipeptide is considered a mixture of two distinct amino acids. Since the amino acids are distinct, based on their composition, two dipeptide's isomers can be produced. Various dipeptides are biologically essential and are therefore crucial to industry.
Trypsin is a digestive enzyme that cleaves proteins into smaller peptide fragments. It does so
by hydrolyzing the amide bond (peptide bond) on the C-terminal side of positively-charged
amino acids. Draw the three hydrolysis products that result when trypsin reacts with the
pentapeptide KINKY at pH 7.4.
Recall: the hydrolysis of amide bonds involves the addition of water. Where does the water
show up in the products of the reaction?
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