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If epigenetic marks were irreversible, it would be impossible to clone an animal from one of its somatic cell nuclei.
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- Why would a mutation in a somatic cell of a multicellular organism not necessarily result in a detectable phenotype?The human phenotype is regulated by epigenetic control of gene expression. Discuss the three main types of epigenetic regulation, illustrating your answer with examples of diseases arising from impairment of each of these processes. 600 words.stion 20 of 20 CO Epigenetics is the study of heritable traits that are not induced by changes to DNA sequence. Epigenetic changes can be inherited during somatic cell division to regulate the daughter cells of an individual organism. Most epigenetic modifications are reset prior to meiosis. However, some epigenetic changes can be inherited across generations. For example, environmental factors such as nutrition and chemical exposure can induce heritable epigenetic changes in animal models (Relton and Davey Smith, 2012). Genome imprinting is one type of epigenetic modification in which a cell or organism can reduce the expression of a gene and thereby silence the gene. Genome imprinting is caused by DNA methylation and histone modification, which reduce expression of a gene. The silencing occurs in a parent-of-origin-specific manner, where either the maternally derived allele or the paternally derived allele is imprinted and silenced. Expression occurs only through the nonimprinted…
- Film name: In the womb: Multiples Question: 1. Explain what epigenetic theory is. 2. From the film, In the Womb: Multiples, select an example where epigenetic theory is at work. Tell what this example is and explain how it is an example of the epigenetic theory. The example must come from the film. Flim main theme & Link: 1. "In the Womb: Multiples" National Geographic Video Summary ( https://studycorgi.com/in-the-womb-multiples-national-geographic-video/#:~:text=The%20video%20shows%20the%20natural,they%20had%20a%20small%20weight. ) 2. National Geographic In The Womb Multiples ( https://www.youtube.com/watch?v=BoMQrVBxa_w ) N.B: Please expert follows those links that I give you.Please explain how the deletion of the same set of genes can result in such different diseases. The example for this question being Prader-willi syndrom and Angelman syndrome. In your answer, be sure to discuss the role of genetic imprinting and epigenetics.Genes with highly similar sequence are often located adjacent one another in the genome. Gene duplication commonly arises from errors in replication. When the organization of such adjacent genes is in an inverted orientation, this can reduce the expression of other genes that have similar sequence and are located on other chromosomes. Explain the mechanism of how this generally occurs. i need a detailed explanation, please. I need to know what the mechanism is. How it happens and why. Please. Thanks
- this is what i have said about this image so far, what else can be said aswell including the raw count column. " Interpreting the results of an RNA-Seq analysis is pivotal in understanding the underlying genetic mechanisms of diseases such as breast cancer. In this analysis, Figure 1 provides comprehensive data on differentially expressed genes associated with breast cancer. By delving into the provided information, we can gain valuable insights into the molecular landscape of this disease. First focus is on the gene with the highest fold change, EYA4, situated on chromosome 6. With a staggering fold change of 3604.4176, EYA4 exhibits an unprecedented level of overexpression in cancerous cells compared to normal cells. This profound alteration suggests a pivotal role for EYA4 in breast cancer pathogenesis. The log2 fold change of 11.81555 further emphasizes the magnitude of this difference in gene expression. Statistical significance is evident, with an exceptionally low p-value of…"once cells have differentiated to their final specialized forms, they never again alter expression of their genes" is true or false.http://www.letsgethealthy.org/students/games/epigenetics-game/ (Links to an external site.) For the assignment this week I want you to play this epigenetic game that will show you how your choices (which will be the equivalent of of external factors in someone life) make your genes act differently. Last week, we learned about biology and race and how these fit together in the formation of biological determinants and social misconceptions. For this week's discussion, play the game. Discuss with your classmates what happened, and what you have learned about epigenetics and how this changes your understanding of genetics . How do epigenetic changes and epigenetic mechanisms in general influence health, our concepts of race, and inequality?
- How might a point mutation in DNA affect the phenotype. How the genome is expressed in the organism? (Please explain this at the molecular level).“In an organism that reproduces asexually, there is no difference between a somatic cell mutation and a germ line mutation.” Is this statement true? Explain.Transmission of information that is not contained within the sequence of DNA to daughter cells at cell division is called epigenetic inheritance. true false