Total number of transformations in the Liver. Total number of transformations in the total body.

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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Inorganic compounds of metallic mercury
are presumed from metabolic studies to
distribute uniformly after inhalation or
ingestion with 8% going to the liver and 92%
to the total body. Biological clearance of
mercury in each of these tissues occurs by
two compartments, 95% with a biological
half-life of 40 days and the remaining 5%
with a biological half-life of 10,000 days. For
an intake of 1 MBq of 203Hg (Tr= 46.61 d).
Determine the following
1. Total number of transformations in
the Liver.
2. Total number of transformations in
the total body.
Transcribed Image Text:Inorganic compounds of metallic mercury are presumed from metabolic studies to distribute uniformly after inhalation or ingestion with 8% going to the liver and 92% to the total body. Biological clearance of mercury in each of these tissues occurs by two compartments, 95% with a biological half-life of 40 days and the remaining 5% with a biological half-life of 10,000 days. For an intake of 1 MBq of 203Hg (Tr= 46.61 d). Determine the following 1. Total number of transformations in the Liver. 2. Total number of transformations in the total body.
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