Thymine dimer 5' 3' 3' The UvrA/UvrB complex tracks along the DNA In search of damaged DNA. 3' 3' 5' After damage is detected, UvrA Is released, and Uvr C binds. 5' Uvr C Uvr C makes cuts on both sides of the thymine dimer. Cut Cut 3' UvrC UvrD, which is a helicase (not shown). removes the damaged reglon. UvrB and UvrCare also released. 5° 3' டட 3' 5' DNA polymerase fills in the gap. and DNA ligase seals the region. No thymine dimer 5' 3' 5' FIGURE 19.18 Nudeotide excision repair in E. coli.
Thymine dimer 5' 3' 3' The UvrA/UvrB complex tracks along the DNA In search of damaged DNA. 3' 3' 5' After damage is detected, UvrA Is released, and Uvr C binds. 5' Uvr C Uvr C makes cuts on both sides of the thymine dimer. Cut Cut 3' UvrC UvrD, which is a helicase (not shown). removes the damaged reglon. UvrB and UvrCare also released. 5° 3' டட 3' 5' DNA polymerase fills in the gap. and DNA ligase seals the region. No thymine dimer 5' 3' 5' FIGURE 19.18 Nudeotide excision repair in E. coli.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Explain why cuts are made on both sides of the damaged region of the DNA.
Transcribed Image Text:Thymine dimer
5'
3'
3'
The UvrA/UvrB complex tracks along the
DNA In search of damaged DNA.
3'
3'
5'
After damage is detected, UvrA
Is released, and Uvr C binds.
5'
Uvr C
Uvr C makes cuts on both
sides of the thymine dimer.
Cut
Cut
3'
UvrC
UvrD, which is a helicase (not shown).
removes the damaged reglon. UvrB
and UvrCare also released.
5°
3'
டட
3'
5'
DNA polymerase fills in the gap.
and DNA ligase seals the region.
No thymine dimer
5'
3'
5'
FIGURE 19.18 Nudeotide excision repair in
E. coli.
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