The total synthesis of the natural product Laurenyne by Larry Overman et al (Ref.: J. Am. Chem. Soc. 1988, 110, 2248) involved the sequence given below for the generation of a conjugated aldehyde. (i) Predict the structures of the intermediates involved. (ii) Outline the mechanism of the Pd-catalysed reaction and identify the named reaction. (i) PCC (ii) Base, TMSOTF (ii) Pd(OAc)2 Но

The total synthesis of the natural product Laurenyne by Larry Overman et al (Ref.: J. Am. Chem. Soc. 1988, 110, 2248) involved the sequence given below for the generation of a conjugated aldehyde. (i) Predict the structures of the intermediates involved. (ii) Outline the mechanism of the Pd-catalysed reaction and identify the named reaction. (i) PCC (ii) Base, TMSOTF (ii) Pd(OAc)2 Но

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter16: Aldehydes And Ketones

Section: Chapter Questions

Problem 16.63P

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