The sd gene causes a lethal disease of infancy in humanswhen homozygous. One in 100,000 newborns die eachyear of this disease. The mutation rate from Sd to sd is2 × 10−4. What must the fitness of the heterozygote be toexplain the observed gene frequency in view of the mutation rate? Assign a relative fitness of 1.0 to Sd /Sd homozygotes. Assume that the population is at equilibriumwith respect to the frequency of sd.

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Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.