The respiratory process involves hemoglobin (Hgb), an iron-containing compound found in red blood cells. In the process, carbon dioxide diffuses from tissue cells as molecular CO2, while O2 simultancously enters the tissue cells. A significant fraction of the CO, leaving the tissue cells enters red blood cells and reacts with hemoglobin; the CO, that does not enter the red blood cells (O in the figure below) remains dissolved in the blood and is transported to the lungs. Some of theCO, entering the red blood cells reacts with hemoglobin to form a compound (Hgb-CO, 2 in the figure). When the red blood cells reach the lungs, the Hgb-CO, dissociates, releasing free CO,. Meanwhile, the CO, that enters the red blood cells but does not react with hemoglobin combines with water to form carbonic acid, H¿CO3, which then dissociates into hydrogen ions and bicarbonate ions (O in the figure). The bicarbonate ions diffuse out of the cells (O in the figure), and the ions are transported to the lungs via the bloodstream. Blood to the lungs.. Red Blood Cell >to the lungs. Dto the lungs. For adult humans, every deciliter of blood transports a total of 1.6 x 10“ mol of carbon dioxide in its various forms (dissolved CO,, Hgb-CO, and bicarbonate ions) from tissues to the lungs under normal, resting conditions. Of the total CO,, 1.1 x 10-ª mol are transported as bicarbonate ions. In a typical resting adult human, the heart pumps approximately 5 liters of blood per minute. You have been asked to determine how many moles of CO, are dissolved in blood and how many moles of Hgb-CO, are transported to the lungs during an hour's worth of breathing. (a) Draw and fully label a flowchart and do a degree-of-freedom analysis. Write the chemical reactions that occur, and generate, but do not solve, a set of independent equations relating the unknown variables on the flowchart. (b) If you have enough information to obtain a unique numerical solution, do so. If you do not have enough information, identify a specific piece/pieces of information that (if known) would allow you to solve the problem, and show that you could solve the problem if that information were known. Exploratory Exercise–Research and Discover (c) When someone loses a great deal of blood due to an injury, they "go into shock": their total blood volume is low, and carbon dioxide is not efficiently transported away from tissues. The carbon dioxide reacts with water in the tissue cells to produce very high concentrations of carbonic acid, some of which can dissociate (as shown in this problem) to produce high levels of hydrogen ions. What is the likely effect of this occurrence on the blood pH near the tissue and the tissue cells? How is this likely to affect the injured person?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
Question
The respiratory process involves hemoglobin (Hgb), an iron-containing compound found in red blood
cells. In the process, carbon dioxide diffuses from tissue cells as molecular CO2, while O2 simultancously
enters the tissue cells. A significant fraction of the CO, leaving the tissue cells enters red blood cells and
reacts with hemoglobin; the CO, that does not enter the red blood cells (O in the figure below) remains
dissolved in the blood and is transported to the lungs. Some of theCO, entering the red blood cells reacts
with hemoglobin to form a compound (Hgb-CO, 2 in the figure). When the red blood cells reach the
lungs, the Hgb-CO, dissociates, releasing free CO,. Meanwhile, the CO, that enters the red blood cells
but does not react with hemoglobin combines with water to form carbonic acid, H¿CO3, which then
dissociates into hydrogen ions and bicarbonate ions (O in the figure). The bicarbonate ions diffuse out of
the cells (O in the figure), and the ions are transported to the lungs via the bloodstream.
Blood
to the lungs..
Red Blood Cell
>to the lungs.
Dto the lungs.
For adult humans, every deciliter of blood transports a total of 1.6 x 10“ mol of carbon dioxide in
its various forms (dissolved CO,, Hgb-CO, and bicarbonate ions) from tissues to the lungs under
normal, resting conditions. Of the total CO,, 1.1 x 10-ª mol are transported as bicarbonate ions. In a
typical resting adult human, the heart pumps approximately 5 liters of blood per minute. You have been
asked to determine how many moles of CO, are dissolved in blood and how many moles of Hgb-CO,
are transported to the lungs during an hour's worth of breathing.
(a) Draw and fully label a flowchart and do a degree-of-freedom analysis. Write the chemical reactions
that occur, and generate, but do not solve, a set of independent equations relating the unknown
variables on the flowchart.
(b) If you have enough information to obtain a unique numerical solution, do so. If you do not have
enough information, identify a specific piece/pieces of information that (if known) would allow
you to solve the problem, and show that you could solve the problem if that information were
known.
Exploratory Exercise–Research and Discover
(c) When someone loses a great deal of blood due to an injury, they "go into shock": their total blood
volume is low, and carbon dioxide is not efficiently transported away from tissues. The carbon
dioxide reacts with water in the tissue cells to produce very high concentrations of carbonic acid,
some of which can dissociate (as shown in this problem) to produce high levels of hydrogen ions.
What is the likely effect of this occurrence on the blood pH near the tissue and the tissue cells? How
is this likely to affect the injured person?
Transcribed Image Text:The respiratory process involves hemoglobin (Hgb), an iron-containing compound found in red blood cells. In the process, carbon dioxide diffuses from tissue cells as molecular CO2, while O2 simultancously enters the tissue cells. A significant fraction of the CO, leaving the tissue cells enters red blood cells and reacts with hemoglobin; the CO, that does not enter the red blood cells (O in the figure below) remains dissolved in the blood and is transported to the lungs. Some of theCO, entering the red blood cells reacts with hemoglobin to form a compound (Hgb-CO, 2 in the figure). When the red blood cells reach the lungs, the Hgb-CO, dissociates, releasing free CO,. Meanwhile, the CO, that enters the red blood cells but does not react with hemoglobin combines with water to form carbonic acid, H¿CO3, which then dissociates into hydrogen ions and bicarbonate ions (O in the figure). The bicarbonate ions diffuse out of the cells (O in the figure), and the ions are transported to the lungs via the bloodstream. Blood to the lungs.. Red Blood Cell >to the lungs. Dto the lungs. For adult humans, every deciliter of blood transports a total of 1.6 x 10“ mol of carbon dioxide in its various forms (dissolved CO,, Hgb-CO, and bicarbonate ions) from tissues to the lungs under normal, resting conditions. Of the total CO,, 1.1 x 10-ª mol are transported as bicarbonate ions. In a typical resting adult human, the heart pumps approximately 5 liters of blood per minute. You have been asked to determine how many moles of CO, are dissolved in blood and how many moles of Hgb-CO, are transported to the lungs during an hour's worth of breathing. (a) Draw and fully label a flowchart and do a degree-of-freedom analysis. Write the chemical reactions that occur, and generate, but do not solve, a set of independent equations relating the unknown variables on the flowchart. (b) If you have enough information to obtain a unique numerical solution, do so. If you do not have enough information, identify a specific piece/pieces of information that (if known) would allow you to solve the problem, and show that you could solve the problem if that information were known. Exploratory Exercise–Research and Discover (c) When someone loses a great deal of blood due to an injury, they "go into shock": their total blood volume is low, and carbon dioxide is not efficiently transported away from tissues. The carbon dioxide reacts with water in the tissue cells to produce very high concentrations of carbonic acid, some of which can dissociate (as shown in this problem) to produce high levels of hydrogen ions. What is the likely effect of this occurrence on the blood pH near the tissue and the tissue cells? How is this likely to affect the injured person?
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps with 2 images

Blurred answer
Knowledge Booster
Hematology
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education