The basolateral surface of the airway epithelium interacts with the extracellular matrix (ECM) and adjacent cells. Integrins stabilize the cell by attaching the cell's cytoskeleton to the ECM. The integrin protein, which passes through the plasma membrane, interacts with the extracellular matrix outside the cell, and the cytoskeleton inside the cell. What best describes how integrins are formed?
The basolateral surface of the airway epithelium interacts with the extracellular matrix (ECM) and adjacent cells. Integrins stabilize the cell by attaching the cell's cytoskeleton to the ECM. The integrin protein, which passes through the plasma membrane, interacts with the extracellular matrix outside the cell, and the cytoskeleton inside the cell. What best describes how integrins are formed?
a.) Integrins are translated by ribosomes attached to the rough endoplasmic reticulum, with their ECM binding site facing the lumen
b.) Integrins are translated by ribosomes attached to the rough endoplasmic reticulum, with their ECM binding site facing away from the lumen
c.) Integrins are translated by ribosomes located in the cytoplasm beneath the apical surface of the cell
d.) Integrins are translated by ribosomes located in the cytoplasm beneath the basolateral surface of the cell
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