The purpose of an investigation by Morley et al. (A-17) was to evaluate the analgesic effective- ness of a daily dose of oral methadone in patients with chronic neuropathic pain syndromes. The researchers used a visual analogue scale (0–100 mm, higher number indicates higher pain) ratings for maximum pain intensity over the course of the day. Each subject took either 20 mg of methadone or a placebo each day for 5 days. Subjects did not know which treatment they were taking. The following table gives the mean maximum pain intensity scores for the 5 days on methadone and the 5 days on placebo. Do these data provide sufficient evidence, at the .05 level of significance, to indicate that in general the maximum pain intensity is lower on days when methadone is taken? Subject Methadone Placebo
Correlation
Correlation defines a relationship between two independent variables. It tells the degree to which variables move in relation to each other. When two sets of data are related to each other, there is a correlation between them.
Linear Correlation
A correlation is used to determine the relationships between numerical and categorical variables. In other words, it is an indicator of how things are connected to one another. The correlation analysis is the study of how variables are related.
Regression Analysis
Regression analysis is a statistical method in which it estimates the relationship between a dependent variable and one or more independent variable. In simple terms dependent variable is called as outcome variable and independent variable is called as predictors. Regression analysis is one of the methods to find the trends in data. The independent variable used in Regression analysis is named Predictor variable. It offers data of an associated dependent variable regarding a particular outcome.
The purpose of an investigation by Morley et al. (A-17) was to evaluate the analgesic effective- ness of a daily dose of oral methadone in patients with chronic neuropathic pain syndromes. The researchers used a visual analogue scale (0–100 mm, higher number indicates higher pain) ratings for maximum pain intensity over the course of the day. Each subject took either 20 mg of methadone or a placebo each day for 5 days. Subjects did not know which treatment they were taking. The following table gives the mean maximum pain intensity scores for the 5 days on methadone and the 5 days on placebo. Do these data provide sufficient evidence, at the .05 level of significance, to indicate that in general the maximum pain intensity is lower on days when methadone is taken?
Subject Methadone
Placebo
1 29.8 57.2
2 73.0 69.8
3 98.6 98.2
4 58.8 62.4
5 60.6 67.2
6 57.2 70.6
7 57.2 67.8
8 89.2 95.6
9 97.0 98.4
10 49.8
Source: John S. Morley, John Bridson, Tim P. Nash, John B.
11 37.0 63.6
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