The preparation of a sulfide from a thiol is analogous to the Williamson ether synthesis. Which of the following describes the mechanism of this transformation? O Three steps: 1) protonation; 2) loss of leaving group; 3) nucleophilic attack. O Deprotonation, followed by SN2. O Three steps: 1) deprotonation; 2) loss of leaving group: 3) nucleophilic attack. O SN2, followed by deprotonation. O Three steps: 1) loss of leaving group; 2) nucleophilic attack; 3) deprotonation.

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Chapter1: Chemical Foundations
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watch the provided video, A Mechanism for Preparation of Sulfides from Thiols by David Klein, and
answer the questions below.
Question 1
The preparation of a sulfide from a thiol is analogous to the Williamson ether synthesis. Which of
the following describes the mechanism of this transformation?
O Three steps: 1) protonation; loss of leaving group; 3) nucleophilic attack.
O Deprotonation, followed by SN2.
O Three steps: 1) deprotonation; 2) loss of leaving group: 3) nucleophilic attack.
O SN2, followed by deprotonation.
O Three steps: 1) loss of leaving group; 2) nucleophilic attack; 3) deprotonation.
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Transcribed Image Text:The following questio watch the provided video, A Mechanism for Preparation of Sulfides from Thiols by David Klein, and answer the questions below. Question 1 The preparation of a sulfide from a thiol is analogous to the Williamson ether synthesis. Which of the following describes the mechanism of this transformation? O Three steps: 1) protonation; loss of leaving group; 3) nucleophilic attack. O Deprotonation, followed by SN2. O Three steps: 1) deprotonation; 2) loss of leaving group: 3) nucleophilic attack. O SN2, followed by deprotonation. O Three steps: 1) loss of leaving group; 2) nucleophilic attack; 3) deprotonation. Save for Later Attempts: 0 of 2 used Submit Answer
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