The pH 6.0 buffer solution had resulted in a higher logD value than the pH 7.0 buffer solution and pH 8.0. This was because the aqueous phase at pH 7.0 was relatively more alkaline than at pH 6.0 and so more acid molecules were ionised and so partitioned more into the aqueous phase at pH 7.0. The outcome of this experiment was therefore determining that benzoic acid is more lipophilic at pH 6.0 than at pH 7.0 and pH 8.0.

The pH 6.0 buffer solution had resulted in a higher logD value than the pH 7.0 buffer solution and pH 8.0. This was because the aqueous phase at pH 7.0 was relatively more alkaline than at pH 6.0 and so more acid molecules were ionised and so partitioned more into the aqueous phase at pH 7.0. The outcome of this experiment was therefore determining that benzoic acid is more lipophilic at pH 6.0 than at pH 7.0 and pH 8.0.

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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