The peptide Leu-Cys-Arg-Ser-Gln-Met is subjected to Edman degradation. In the first cycle the peptide first reacts with phenylisothiocyanate under basic conditions. The product of this reaction is incubated with anhydrous trifluoroacetic acid and subsequently with an aqueous acid. What are the products generated in the first cycle. PTH-Leu-Cys-Arg-Ser-Gln-Met PTH-Leu, PTH-Cys, PTH-Arg, PTH-Ser, PTH-GIn, and PTH-Met PTH-Leu and Cys-Arg-Ser-Gln-Met PTH-Met and Leu-Cys-Arg-Ser-GIn-Met PTH-Leu-Cys and PTH-Arg-Ser-Gln-Met O O O O

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Chapter1: Biochemistry: An Evolving Science
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QUESTION 20
The peptide Leu-Cys-Arg-Ser-Gln-Met is subjected to Edman degradation. In the first cycle the peptide
first reacts with phenylisothiocyanate under basic conditions. The product of this reaction is incubated with
anhydrous trifluoroacetic acid and subsequently with an aqueous acid. What are the products generated in
the first cycle.
O PTH-Leu-Cys-Arg-Ser-Gln-Met
PTH-Leu, PTH-Cys, PTH-Arg, PTH-Ser, PTH-GIn, and PTH-Met
PTH-Leu and Cys-Arg-Ser-Gln-Met
PTH-Met and Leu-Cys-Arg-Ser-Gln-Met
PTH-Leu-Cys and PTH-Arg-Ser-GIn-Met
O O O O O
Transcribed Image Text:QUESTION 20 The peptide Leu-Cys-Arg-Ser-Gln-Met is subjected to Edman degradation. In the first cycle the peptide first reacts with phenylisothiocyanate under basic conditions. The product of this reaction is incubated with anhydrous trifluoroacetic acid and subsequently with an aqueous acid. What are the products generated in the first cycle. O PTH-Leu-Cys-Arg-Ser-Gln-Met PTH-Leu, PTH-Cys, PTH-Arg, PTH-Ser, PTH-GIn, and PTH-Met PTH-Leu and Cys-Arg-Ser-Gln-Met PTH-Met and Leu-Cys-Arg-Ser-Gln-Met PTH-Leu-Cys and PTH-Arg-Ser-GIn-Met O O O O O
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