The loss of CO2 (decarboxylation) from a ß-keto acid happens frequently in biological chemistry and takes place by a mechanism that is closely related to a retroaldol reaction. Propose a mechanism for the following reaction assuming there is an active site acid (HA) available: hel CH,CO2 D₂C B -0₂C CO₂ + CO₂

The loss of CO2 (decarboxylation) from a ß-keto acid happens frequently in biological chemistry and takes place by a mechanism that is closely related to a retroaldol reaction. Propose a mechanism for the following reaction assuming there is an active site acid (HA) available: hel CH,CO2 D₂C B -0₂C CO₂ + CO₂

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter11: Reactions Of Alkyl Halides: Nucleophilic Substitutions And Eliminations

Section11.SE: Something Extra

Problem 35MP: One step in the urea cycle for ridding the body of ammonia is the conversion of argininosuccinate to...

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