The loss of CO2 (decarboxylation) from a ß-keto acid happens frequently in biological chemistry and takes place by a mechanism that is closely related to a retroaldol reaction. Propose a mechanism for the following reaction assuming there is an active site acid (HA) available: hel CH,CO2 D₂C B -0₂C CO₂ + CO₂
The loss of CO2 (decarboxylation) from a ß-keto acid happens frequently in biological chemistry and takes place by a mechanism that is closely related to a retroaldol reaction. Propose a mechanism for the following reaction assuming there is an active site acid (HA) available: hel CH,CO2 D₂C B -0₂C CO₂ + CO₂
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:The loss of CO2 (decarboxylation) from a ß-keto acid happens frequently in
biological chemistry and takes place by a mechanism that is closely related to
a retroaldol reaction. Propose a mechanism for the following reaction
assuming there is an active site acid (HA) available:
hel
CH2CO2
0₂C B
-0₂C
CO₂
+
CO₂
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