Glucuronic acid is an oxidized derivative of glucose found in animal secretions such as saliva. Biological conversion of glucuronic acid into its isomer, fructuronic acid, is catalyzed by an enzyme called uronic acid isomerase. OH HO HOʻ H20, H* HỌ HO Но ОН ОН uronic acid isomerase HO ОН fructuronic acid glucuronic acid Provide a complete curved-arrow mechanism for this transformation. You may assume that the enzyme active site will supply all necessary equivalents of water and acid in order to accomplish the reaction. (In other words, draw the mechanism as if the only reagents were H3O* and H20.)
Glucuronic acid is an oxidized derivative of glucose found in animal secretions such as saliva. Biological conversion of glucuronic acid into its isomer, fructuronic acid, is catalyzed by an enzyme called uronic acid isomerase. OH HO HOʻ H20, H* HỌ HO Но ОН ОН uronic acid isomerase HO ОН fructuronic acid glucuronic acid Provide a complete curved-arrow mechanism for this transformation. You may assume that the enzyme active site will supply all necessary equivalents of water and acid in order to accomplish the reaction. (In other words, draw the mechanism as if the only reagents were H3O* and H20.)
Chemistry
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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:Glucuronic acid is an oxidized derivative of glucose found in animal secretions such as saliva. Biological
conversion of glucuronic acid into its isomer, fructuronic acid, is catalyzed by an enzyme called uronic acid
isomerase.
OH
HO
HO
H20, H*
НО
Но-
Но-
НО
HO
uronic acid isomerase
Но
ОН
fructuronic acid
glucuronic acid
Provide a complete curved-arrow mechanism for this transformation. You may assume that the enzyme
active site will supply all necessary equivalents of water and acid in order to accomplish the reaction. (In other
words, draw the mechanism as if the only reagents were H3O* and H20.)
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