The light-chain genes remain in the germline configuration. (Select all that apply.) Stem cell Early pro-B cell Late pro-B cell Large pre-B cell Small pre-B cell Immature B cell Mature naive B cell

Q: A congenital defect mutates the genes that code for RAG1 & RAG2 making them unreadable (therefore no…

A:

Q: Match the term with its correct description. Transcription factor required for T-cell development…

A: The different terms mentioned in the question are related to the development and formation of the T…

Q: Describe early activity of naïve B and T cells leading to clonal expansion.

A: Naive B cells - these are present in spleen as well as human tonsil and is small cells which express…

Q: Match the following terms of B-cell development with the best definition. Surrogate light chain…

A: The immune system of the body is the vital system that provides protection to the body against…

Q: Match the term with its correct description. Transcription factor required for T-cell development…

A: Introduction T-cells are the important immune cells that are developed in the Thymus. These are…

Q: An A negative mother (gravida 5, para 5) has just delivered an A positive newborn.  Her antibody…

A: RH immune globulinis a concentrated immunoglobulin preparation that contains antibodies to Rh. These…

Q: Briefly, what are the 2 ‘checkpoints’ in development for the B cell? When do the B cells pause to…

A: In humans, B-cells are a type of WBCs (white blood cells) involved in the humoral immunity…

Q: 1.helper T cells 2.B cells 3.Cytotoxic T cells 4.memory B and T cells…

A: Correct answer: 1 - A & B 2- C 3- E 4- D

Q: Class switching is initiated by T-cell activation via CD40 ligation. You are working with a mouse…

A: Class switching, also known as isotype switching, is a process in B cells that involves changing the…

Q: Transcription factor required for T-cell development Composed of superdimer, CD3 and zeta chain…

A: E2A and HEB, which are members of the basic helix–loop–helix (bHLH) transcription factor family,…

Q: Cytokine associated with development of autism is- IFN-gamma O TNF-alpha O IL-6 O IL=1 beta

A: Cytokine These are small proteins that are involved in cell signalling. These are the components…

Q: D. TH17 17. Down regulation of ..............allow naïve T cells to enter lymph nodes? B. B7 C.…

A: T cells These are white blood cells that belong to the adaptive immune system. These cells play a…

Q: Describe what is assembled on the surface of pre-B cells.

A: Pre B cells are cells in the bone marrow that are progenators of the B cells that are a part of the…

Q: How can a B cell have both IgM and IgD on its surface?

A: * B cells produce from lymphoid progenitor cell which develop in fetal liver and later in bone…

Q: Explain each of the ways that the immune system has a mechanism of control in the development and…

A: Note: As per guidelines, we can answer one question at a time. Ask rest to get answers  Introduction…

Q: Match the best choice of information about immunoglobulliins with the IG match The answer options…

A: Immunoglobulin are antibody molecules which are made up of carbohydrates and proteins. They are main…

Q: Match the antibody class to its correct description. Select the INCORRECT choice. a. IgE / the…

A: Immune system protects the body against foreign antigens and pathogens. Antibodies are proteins…

Q: The absence of _______ at birth will affect the maturation of T cells.     D     C     B     A…

A: Lymphatic system is composed of lymph, lymphatic organs and lymphatic vessels. Spleen, thymus, lymph…

Q: What is the rate-limiting step that causes the death of approximately 50% of transitional B cells…

A: B cells or B lymphocytes are important players in the adaptive immune response that is responsible…

Q: What two functions do the follicular dendritic cells provide B cells?

A: Follicular dendritic cells or FDC s are one type of specialized antigen presenting dendritic cell…

Q: Which of the following statements are accurate? T cells, B cells, and Natural killer cells are…

A: According to guidelines we have to answer the first question only. so please kindly post the…

Q: If fetal T cells respond so vigorously against alloantigens in vitro, would they no also respond…

A: Fetal T cells display strong responses against alloantigens when tested in vitro. However, a vital…

Q: True

A: Introduction :- B- cell (B lymphocyte) is one of the most important cell of the body. They form a…

Q: True or false: 1. Highly proliferative centroblasts are located in the light-zone rather than the…

A: Different types of memory cells, including central memory effector memory & tissue-resident…

Q: What are two types of long-lived cells derived from the B cell lineage? Where are these cells…

A: B cells are a type of white blood cell that helps the immune system fight foreign invaders including…

Q: During fetal development, T and B lymphocytes undergo a process that prepares them to react only to…

A: B cells are type of lymphocyte that fight bacteria and viruses by making Y -shaped proteins called…

Q: Where do B-cells proliferate and mature? Group of answer choices Thymus Red bone marrow Liver Small…

A: B-cells are also called B lymphocytes. These are types of white blood cells of the lymphocyte…

Q: What is the function of interleukin-7 in lymphocyte formation? View Available Hint(s) Hint 1.…

A: Interleukin -7 is necessary for the growth, viability, and homeostasis of T-cells. These…

Q: B cells - A comparison of B and T cell maturation. List the locations and what is happening…

A: B and T cells, fundamental components of the adaptive immune system, undergo a structured maturation…

Q: The selection process for T cells is more complex than B cells. Please explain the process, why it…

A: B cells and T cells from the basis of adaptive immunity. These form two broad classes of specific…