The interactions between theophylline and two other drugs (famotidine and cimetidine) were studied in fourteen patients with chronic obstructive pulmonary disease. Of particular interest were the pharmacokinetics of theophylline when it was being taken simultaneously with each drug. The study was conducted in three periods: one with theophylline and placebo, a second with theophylline and famotidine, and the third with theophylline and cimetidine. One outcome of interest is the clearance of theophylline (liters/hour). Interacting Drug Subject Cimetidine Famotidine Placebo 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Standard deviation min Q1 3.69 3.61 Q3 1.15 4.02 1.00 1.45 2.59 1.57 2.34 1.75 2.11 1.31 Mean 2.26 2.43 2.33 2.34 0.97 1.00 1.42 median 2.34 2.85 5.13 max 4.02 7.04 1.46 4,44 1.15 2.12 3.25 2.11 5.2 1.98 2.38 3.53 2.33 3.16 1.70 1.15 2.08 2.36 4.61 7.04 5.88 5.89 1.46 4.05 1.09 2.59 1.69 3.16 2.06 4.59 2.08 2.61 3.42 2.54 3.08 1.53 1.09 1.97 2.60 4.19 5.89 Create side-by-side boxplots of the three drugs and mark down the sample means on the plots.

The interactions between theophylline and two other drugs (famotidine and cimetidine) were studied in fourteen patients with chronic obstructive pulmonary disease. Of particular interest were the pharmacokinetics of theophylline when it was being taken simultaneously with each drug. The study was conducted in three periods: one with theophylline and placebo, a second with theophylline and famotidine, and the third with theophylline and cimetidine. One outcome of interest is the clearance of theophylline (liters/hour). Interacting Drug Subject Cimetidine Famotidine Placebo 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Standard deviation min Q1 3.69 3.61 Q3 1.15 4.02 1.00 1.45 2.59 1.57 2.34 1.75 2.11 1.31 Mean 2.26 2.43 2.33 2.34 0.97 1.00 1.42 median 2.34 2.85 5.13 max 4.02 7.04 1.46 4,44 1.15 2.12 3.25 2.11 5.2 1.98 2.38 3.53 2.33 3.16 1.70 1.15 2.08 2.36 4.61 7.04 5.88 5.89 1.46 4.05 1.09 2.59 1.69 3.16 2.06 4.59 2.08 2.61 3.42 2.54 3.08 1.53 1.09 1.97 2.60 4.19 5.89 Create side-by-side boxplots of the three drugs and mark down the sample means on the plots.

MATLAB: An Introduction with Applications

6th Edition

ISBN:9781119256830

Author:Amos Gilat

Publisher:Amos Gilat

Chapter1: Starting With Matlab

Section: Chapter Questions

Problem 1P

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