The inner mitochondrial membrane is damaged, and it becomes increasingly permeable to hydrogen ions. Which of the following statements IS NOT true. The H+ gradient stored in the matrix created by the electron transport chain dissipates when H+ ions diffuse into the inner mitochondrial membrane space. Complex I, II, III and IV are still able to pump H+ into the inner mitochondrial membrane space due to the oxidation of NADH and FADH2. The H+ ions pumped into the inner mitochondrial membrane space are not efficiently used by ATP synthase to generate ATP. As a result, the production of ATP for every molecule of pyruvate that enters the mitochondrion is reduced.

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Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.