The image below shows the citric acid cycle. Reactions (3) and (4) are referred to as "oxidative". What does this mean? Select the correct statement Dehydrogenation HO–CH Malate 7 Hydration H₂0 malate Coo- dehydro- genase CH₂ COO™ HC соо- Fumarate CH I fumarase COO 0-c-co CH₂-COO™ Oxaloacetate FADH₂ succinate dehydrogenase Dehydrogenation CH₂-COO- L CH ₂ COO™ Succinate CoA-SH Acetyl-CoA CH3-C-S-COA H₂O GTP (5) (ATP) Substrate-level citrate synthase succinyl-CoA synthetase Citric acid cycle NADH Condensation CH₂-COO™ CH₂ GDP C-S-COA (ADP) + P₁ Succinyl-CoA CoA-SH CH₂-COO™ --co (2a) CH₂-COO Dehydration Citrate H₂O a-ketoglutarate dehydrogenase CO2 aconitase CoA-SH CH₂-COO- c-coo- c-coo aconitase HO-C-H I isocitrate dehydrogenase/ Coo- complex CH₂-COO™ CH₂- CH₂ C-O COO™ Oxidative decarboxylation cis-Aconitate H₂O CH₂-COO™ H-C-COO™ CO₂ 2b Hydration Isocitrate Oxidative decarboxylation a-ketoglutarate

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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The image below shows the citric acid cycle. Reactions (3) and (4) are referred to as
"oxidative". What does this mean? Select the correct statement
Dehydrogenation
HO–CH
Malate
Hydration
H₂O
malate
coo- dehydro-
genase
CH₂
1/ COO
0-c-coo
ÇOO™
Fumarate CH
HC
fumarase
CH₂-COO™
Oxaloacetate
FADH₂
Succinate
succinate
dehydrogenase
Dehydrogenation CH₂-COO-
CH ₂
COO™
CoA-SH
Acetyl-CoA
GTP
(ATP)
CH3-C-S-COA H₂O
(5)
Substrate-level
phosphorylation
succinyl-CoA
synthetase
citrate
synthase
Citric acid
cycle
Figure 16-7
Lehringer Brinciples of Biochemistry Fifth Edition
Condensation
NADH
CH₂-COO™
CH₂
GDP C-S-COA
(ADP) O
+ P₁
CoA-SH
CH₂-COO™
HỌ—C—C00
2a
CH₂-COO Dehydration
Citrate
H₂O
CO2
aconitase
a-ketoglutarate
dehydrogenase
CoA-SH
CH₂-COO™
C-COO-
-COO
aconitase
HO-C-H
isocitrate
dehydrogenase/ Coo-
complex CH₂-COO
CH₂
C=O
COO™
H₂O
Ho
CH₂-COO™
Oxidative
Succinyl-CoA decarboxylation
H-C-COO
cis-Aconitate
CO₂
(2b)
Hydration
Isocitrate
Oxidative
decarboxylation
a-ketoglutarate
Transcribed Image Text:The image below shows the citric acid cycle. Reactions (3) and (4) are referred to as "oxidative". What does this mean? Select the correct statement Dehydrogenation HO–CH Malate Hydration H₂O malate coo- dehydro- genase CH₂ 1/ COO 0-c-coo ÇOO™ Fumarate CH HC fumarase CH₂-COO™ Oxaloacetate FADH₂ Succinate succinate dehydrogenase Dehydrogenation CH₂-COO- CH ₂ COO™ CoA-SH Acetyl-CoA GTP (ATP) CH3-C-S-COA H₂O (5) Substrate-level phosphorylation succinyl-CoA synthetase citrate synthase Citric acid cycle Figure 16-7 Lehringer Brinciples of Biochemistry Fifth Edition Condensation NADH CH₂-COO™ CH₂ GDP C-S-COA (ADP) O + P₁ CoA-SH CH₂-COO™ HỌ—C—C00 2a CH₂-COO Dehydration Citrate H₂O CO2 aconitase a-ketoglutarate dehydrogenase CoA-SH CH₂-COO™ C-COO- -COO aconitase HO-C-H isocitrate dehydrogenase/ Coo- complex CH₂-COO CH₂ C=O COO™ H₂O Ho CH₂-COO™ Oxidative Succinyl-CoA decarboxylation H-C-COO cis-Aconitate CO₂ (2b) Hydration Isocitrate Oxidative decarboxylation a-ketoglutarate
Oxygen is produced as part of the two reactions
O These reactions can only continue under aerobic conditions
O It is another term used to describe alternate reactions to acetylation
Electrons are lost from the substrate and transferred to electron acceptors
O Carbon dioxide is released in exchange for oxygen
Transcribed Image Text:Oxygen is produced as part of the two reactions O These reactions can only continue under aerobic conditions O It is another term used to describe alternate reactions to acetylation Electrons are lost from the substrate and transferred to electron acceptors O Carbon dioxide is released in exchange for oxygen
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