The formation of glutamine from glutamate and ammonium ions requires 14.2 kJ mol of energy input. It is driven by the hydrolysis of ATP to ADP mediated by the enzyme glutamine synthetase. (a) Given that the change in Gibbs energy for the hydrolysis of ATP corresponds to AG-31 kl mol under the conditions prevailing in a typical cell, can the hydrolysis drive the formation of glutamine? (b) How many moles of ATP must be hydrolysed to form 1 mol of glutamine?
The formation of glutamine from glutamate and ammonium ions requires 14.2 kJ mol of energy input. It is driven by the hydrolysis of ATP to ADP mediated by the enzyme glutamine synthetase. (a) Given that the change in Gibbs energy for the hydrolysis of ATP corresponds to AG-31 kl mol under the conditions prevailing in a typical cell, can the hydrolysis drive the formation of glutamine? (b) How many moles of ATP must be hydrolysed to form 1 mol of glutamine?
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:The formation of glutamine from glutamate and ammonium ions requires 14.2 kJ mol of
energy input. It is driven by the hydrolysis of ATP to ADP mediated by the enzyme glutamine
synthetase.
(a) Given that the change in Gibbs energy for the hydrolysis of ATP corresponds to AG-31 kl
mol under the conditions prevailing in a typical cell, can the hydrolysis drive the formation
of glutamine?
(b) How many moles of ATP must be hydrolysed to form 1 mol of glutamine?
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