The following three derivatives of succinimide are anticonvulsants and have found use in the treatment of epilepsy, particularly petit mal seizures.PhPh`N'`N'ČH3ČH3MethsuximideEthosuximidePhensuximideFollowing is a synthesis of phensuximide.CNPhCNPhCN1. NaOH, H2O2. HC, Н20NaOEtKCNPh-CHOcOOEtHcOOEtNCCOOEt3. НeatEthylcyanoacetate(A)(B)BenzaldehydePhPhPhCH;NH2НООССООНEt0oCCOOEt`N'(C)(D)ČH3PhensuximideMethsuximide is formed by a similar pathway to that shown for phensuximide. Draw the structure of the compound that reacts with ethyl cyanoacetate in the synthesis ofmethsuximide.

Starting from benzaldehyde we get phensuccimide that has a phenyl group and an H at carbon alpha to…

The following three derivatives of succinimide are anticonvulsants and have found use in the treatment of epilepsy, particularly petit mal seizures. Ph Ph O: 'N. ČH3 ČH3 Methsuximide Ethosuximide Phensuximide Following is a synthesis of phensuximide. CN Ph CN Ph CN NaOEt KCN 1. NaOH, H2O Ph-CHO 2. HCI, H2O 3. Нeat COOET COOEt NC COOE. Ethyl cyanoacetate (A) (B) Benzaldehyde Ph Ph Ph CH;NH2 НООС COOH Et0OC COOEt (C) (D) CH3 Phensuximide Methsuximide is formed by a similar pathway to that shown for phensuximide. Draw the structure of the compound that reacts with ethyl cyanoacetate in the synthesis of methsuximide.

The following three derivatives of succinimide are anticonvulsants and have found use in the treatment of epilepsy, particularly petit mal seizures. Ph Ph O: 'N. ČH3 ČH3 Methsuximide Ethosuximide Phensuximide Following is a synthesis of phensuximide. CN Ph CN Ph CN NaOEt KCN 1. NaOH, H2O Ph-CHO 2. HCI, H2O 3. Нeat COOET COOEt NC COOE. Ethyl cyanoacetate (A) (B) Benzaldehyde Ph Ph Ph CH;NH2 НООС COOH Et0OC COOEt (C) (D) CH3 Phensuximide Methsuximide is formed by a similar pathway to that shown for phensuximide. Draw the structure of the compound that reacts with ethyl cyanoacetate in the synthesis of methsuximide.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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