The first reaction of fatty acid synthesis is a carboxylation. The mechanism of this C-C bond- forming reaction is similar to • the reverse of the decarboxylation reaction that takes place in pyruvate decarboxylase forming acetaldehyde from pyruvate the aldol cleavage reaction that takes place during glycolysis the carboxylation of pyruvate converting it to oxaloacetate the reverse of the B-decarboxylation reaction that occurs in the second half of the isocitrate dehydrogenase reaction converting isocitrate to a-ketoglutarate

The first reaction of fatty acid synthesis is a carboxylation. The mechanism of this C-C bond- forming reaction is similar to • the reverse of the decarboxylation reaction that takes place in pyruvate decarboxylase forming acetaldehyde from pyruvate the aldol cleavage reaction that takes place during glycolysis the carboxylation of pyruvate converting it to oxaloacetate the reverse of the B-decarboxylation reaction that occurs in the second half of the isocitrate dehydrogenase reaction converting isocitrate to a-ketoglutarate

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter18: Glycolysis

Section: Chapter Questions

Problem 6P: The Reactions and Meehanisms of the Leloir Pathway Write the reactions that permit galactose to be...

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Question

Explain

The first reaction of fatty acid synthesis is a carboxylation. The mechanism of this C-C bond-
forming reaction is similar to
• the reverse of the decarboxylation reaction that takes place in pyruvate decarboxylase forming acetaldehyde
from pyruvate
the aldol cleavage reaction that takes place during glycolysis
the carboxylation of pyruvate converting it to oxaloacetate
the reverse of the B-decarboxylation reaction that occurs in the second half of the isocitrate dehydrogenase
reaction converting isocitrate to a-ketoglutarate

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