The diagram shown represents the coding strand of the myosin gene. Mutations in myosin can lead to muscle defects during development. Using what you know about how mutations can affect transcriptional and post-transcriptional regulation, match the results shown on the Northern (mature MRNA) to the mutations shown. The N lane shows the size and amount expected for non-mutated myosin mRNA. All samples were loaded at the top (-) side of the gel. Part 1. Which lane or lanes on the gel could be the result of mutation A? ТАТАА AUG UAA Only known regulatory region TSS Mutation B: Mutation C. 3 nucleotides A: 5-base deletion 20 nucleotides deleted changed 1 2 3 4 lane 1 lane 2 lane 3 lane 4 lane 5 O00O0
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
A heritable genetic change in the genetic material of an organism that gives rise to alternate forms of any gene is called mutation. Gene mutation can occur due to many reasons, like change in chromosome number, chromosomal aberrations, chemical change in the nucleotide structure of gene, etc.
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