The compound trans-1,2- chlorocyclohexane exists as two terconverting chair conformations shown. Calculate the difference in energy (AG) due 1,3-diaxial strain (A-values provided). Substituent -F -CI -CH3 -CH(CH3)2 -C(CH3)3 CI CI CI 1,3-diaxial strain AG (kcal/mol) 0.2 0.5 1.8 2.1 5.4

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The compound trans-1,2-
chlorocyclohexane exists as two
interconverting chair conformations shown.
Calculate the difference in energy (AG) due
to 1,3-diaxial strain (A-values provided).
Substituent
-F
-CI
-CH3
-CH(CH3)2
-C(CH3)3
11
CI
CI
CI
-CI
1,3-diaxial strain
AG (kcal/mol)
0.2
0.5
1.8
2.1
5.4
kcal/mol
Transcribed Image Text:The compound trans-1,2- chlorocyclohexane exists as two interconverting chair conformations shown. Calculate the difference in energy (AG) due to 1,3-diaxial strain (A-values provided). Substituent -F -CI -CH3 -CH(CH3)2 -C(CH3)3 11 CI CI CI -CI 1,3-diaxial strain AG (kcal/mol) 0.2 0.5 1.8 2.1 5.4 kcal/mol
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