The coenzyme NAD+ or NADH has the following characteristics (Choose all that apply)O oxidizes carboxyl groups to aldehydesO oxidizes hydroxyl functional groups to carbonyl functional groupsis not easily oxidized, stable in the oxygen environment of the mitochondrial matrixO is a mobile carrier of high energy phosphoryl groupsis easily oxidized, unstable in the oxygen environment of the mitochondrial matrixis a mobile carrier of high energy reducing equivalents, hydride ionsaccepts electrons as a proton H* (2 electrons)O accepts electrons as a hydride ion (2 electrons)

Answered: The coenzyme NAD+ or NADH has the…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Question

The coenzyme NAD+ or NADH has the following characteristics (Choose all that apply)
O oxidizes carboxyl groups to aldehydes
O oxidizes hydroxyl functional groups to carbonyl functional groups
is not easily oxidized, stable in the oxygen environment of the mitochondrial matrix
O is a mobile carrier of high energy phosphoryl groups
is easily oxidized, unstable in the oxygen environment of the mitochondrial matrix
is a mobile carrier of high energy reducing equivalents, hydride ions
accepts electrons as a proton H* (2 electrons)
O accepts electrons as a hydride ion (2 electrons)

Expert Solution

Step 1: Reactions involving NAD+ and NADH

NAD⁺ is a cofactor of many enzymes that catalyze redox reactions. A hydride ion is transferred from a substrate to NAD⁺. This oxidizes the substrate and reduces NAD⁺ to NADH.

XH₂ + NAD⁺ $rightwards harpoon over leftwards harpoon$ X + NADH + H⁺

'XH₂' is the substrate in the forward direction.

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