The cell cycle contains a series of events that control the division of cells. It is controlled by which of the following: P. dephosphorylation of cyclin-dependent kinases (S) Q. binding of CDK inhibitor proteins (R) R. cyclin synthesis and degradation (P) S. phosphorylation of cyclin-dependent kinases (Q) R and S
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- You are studying three proteins that you think are important Yor progression through the cell cycle. You know that one of them is a phosphatase (P1) and the other two are kinases ( K1 and K2). You add these enzymes in different combinations as shown below, and find that they have different effects on the activity of a cyclin dependent kinase, cdk2p. cdk2p Inactive Active cdk2p + K1 cdk2p + K2 Inactive cdk2p + K1 + K2 Inactive cdk2p + P1 cdk2p + P1 + K2 cdk2p + P1 + K1 Inactive Inactive Active cdk2p + P1 + K1 + K2 ActiveThe cell cycle contains a series of events that control the division of cells. It is controlled by which of the following: P. dephosphorylation of cyclin-dependent kinases (S) Q. binding of CDK inhibitor proteins (R) R. cyclin synthesis and degradation (P) S. phosphorylation of cyclin-dependent kinases (Q) Q and R P, Q, R, and S R and S P and Q OProgression through the cell cycledepends on the phosphorylationof hundreds of different proteins bycyclin–Cdk complexes. What are themolecular mechanisms ensuring thatthese proteins are phosphorylated atprecisely the right time and place?
- What from mitosis is triggered by mitotic CDK inactivationmainly brought about by mitotic cyclin degradation.(46) A mutated form of protein p5x is found in patients with squamous cell carcinoma. In vitro studies show that the normal p5x molecule binds to DNA, and neoplastic cells accumulate in the G0 phase of the cell cycle. In contrast, the mutated form of p5x does not bin d to DNA. These finding are most characteristics of which of the following? (A) Growht factor receptors (B) GTP-binding protein (C) Nonreceptor tyrosine kinases (D) Oncogene proteins (E) Tumor suppressor gene proteins13) A phosphotase removes an inhibitory phosphotyrosine phosphate from the serine protein kinase, in MPF whcih activates the kinase and triggers the initiation of mitosis. true or false
- in term of signal transduction how cell cycle/division is controlled?? ((while you are answerig plz write the refrence.))Which of the following would result in cell cycle arrest? O phosphorylation of Rb by G1-Cdk phosphorylation of p53 O phosphorylation of helicase by S-Cdk phosphorylation of M-Cdk by CAK phosphorylation of APC by M-CdkArtificially induced apoptosis (controlled cellular death) is found to be an effective treat- ment for some forms of cancer. Which of the following describes the most likely mechanism by which apoptosis might be induced? A B с D by causing ribosomes to increase the rate of protein synthesis by triggering the division of mitochondria in the cell to increase ATP production by increasing the expression of membrane-bound glucose protein channels by causing lysosomes to release digestive enzymes into the cytosol
- (a) the cell cycle is divided into different phases (referred to as M, G0, G1, S and G2); Can you account for what happens during the different parts of the cycle and out of it is checked? ( b) What is the difference between apoptosis and necrosis? ( c) What are caspases and what is their function in the cell?What cellular mechanism(s) ensure that passage through the cell cycle is unidirectional and irreversible? What mo-lecular machinery underlies these mechanism(s)?Cell specializations are usually a modification or elaboration of one of the basic cell functions. (True or fa1se?)