The article “Improved Bioequivalence Assessment of Topical Dermatological Drug Products Using Dermatopharmacokinetics” (B. N’Dri-Stempfer, W. Navidi, et al., Pharmaceutical Research, 2009:316–328) describes a study in which a new type of ointment was applied to forearms of volunteers to study the rates of absorption into the skin. Eight locations on the forearm were designated for ointment application. The new ointment was applied to four locations, and a control was applied to the other four. How many different choices were there for the four locations to apply the new ointment?
Contingency Table
A contingency table can be defined as the visual representation of the relationship between two or more categorical variables that can be evaluated and registered. It is a categorical version of the scatterplot, which is used to investigate the linear relationship between two variables. A contingency table is indeed a type of frequency distribution table that displays two variables at the same time.
Binomial Distribution
Binomial is an algebraic expression of the sum or the difference of two terms. Before knowing about binomial distribution, we must know about the binomial theorem.
The article “Improved Bioequivalence Assessment of Topical Dermatological Drug Products Using Dermatopharmacokinetics” (B. N’Dri-Stempfer, W. Navidi, et al., Pharmaceutical Research, 2009:316–328) describes a study in which a new type of ointment was applied to forearms of volunteers to study the rates of absorption into the skin. Eight locations on the forearm were designated for ointment application. The new ointment was applied to four locations, and a control was applied to the other four. How many different choices were there for the four locations to apply the new ointment?
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