The alleles his-5 and lys-1, found in yeast, result in cells that require histidine and lysine for growth, respectively.  A cross was made between two haploid yeast strains that are his-5 lys-1 and his+ lys+.  973 tetrads were analyzed, with the follow pattern:   7 tetrads with 2 his-5 lys+ spores and 2 his+ lys-1 spores 603 tetrads with 2 his-5 lys-1 spores and 2 his+ lys+ spores 363 tetrads with 1 his-5 lys-1 spore, 1 his-5 lys+ spore, 1 his+ lys-1 spores, and 1 his+ lys+ spore   Compute the map distance between these two genes using the method that considered double crossovers and the one that does not.  Which gives the higher value?  Why?   What is the frequency of single crossovers between these genes?  Explain.   Based on the frequency of single-crossovers, how many double crossovers would one expect?  Is positive interference occurring?

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Inheritance and Mendelian Genetics

Inheritance means the passing of traits to offspring from parents. These traits could be passed either through asexual reproduction or sexual reproduction. The offspring receives the genetic material from the parents. Mendelian inheritance is a certain biological inheritance that follows the rules and principles laid down by Gregor Mendel in 1865. The initial hypothesis was considered wrong, but other inheritance theories modified the concept of inheritance and thus genetics.