The ABO blood group in humans is controlled by a single locus with three different alleles. Homozygosity for IA produces type A blood. Homozygosity for IB produces type B blood. Homozygosity for IO produces type O blood. Type AB blood is produced by the genotype IA/IB. IO is recessive to IA and IB; thus, IA/IO gives type A blood and IB/IO gives type B blood. In the United States, the allele frequencies for the ABO alleles are given below. The Rh factor in blood typing also has multiple alleles, but the alleles can be classified into two types, positive and negative. Rh+ is dominant over Rh−. The allele frequencies of these alleles are also indicated below. The MN blood antigen trait is controlled by two codominant alleles at a single locus. Type M individuals are homozygous for the M allele, type MN individuals are heterozygous, and type N individuals are homozygous for the N allele (codominant). In the United States, the allele frequencies for this blood group are also indicated below. ABO Rhesus MN [IO] = 0.50 [IA] = 0.35 [IB] = 0.15 [Rh+] = 0.6 [Rh-] = 0.4 [M] = 0.5 N = 0.5 At what frequency would you expect to find type M blood among progeny from brother-sister mating? 0.5 0.22 0.27 0.31 0.25 not correct
The ABO blood group in humans is controlled by a single locus with three different alleles. Homozygosity for IA produces type A blood. Homozygosity for IB produces type B blood. Homozygosity for IO produces type O blood. Type AB blood is produced by the genotype IA/IB. IO is recessive to IA and IB; thus, IA/IO gives type A blood and IB/IO gives type B blood. In the United States, the allele frequencies for the ABO alleles are given below. The Rh factor in blood typing also has multiple alleles, but the alleles can be classified into two types, positive and negative. Rh+ is dominant over Rh−. The allele frequencies of these alleles are also indicated below. The MN blood antigen trait is controlled by two codominant alleles at a single locus. Type M individuals are homozygous for the M allele, type MN individuals are heterozygous, and type N individuals are homozygous for the N allele (codominant). In the United States, the allele frequencies for this blood group are also indicated below.
ABO Rhesus MN
[IO] = 0.50
[IA] = 0.35
[IB] = 0.15 [Rh+] = 0.6
[Rh-] = 0.4 [M] = 0.5
N = 0.5
At what frequency would you expect to find type M blood among progeny from brother-sister mating?
0.5
0.22
0.27
0.31
0.25 not correct
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