Synthesis. Design a synthetic route to perform the transformations shown below. You may use any other reagents necessary, as long as the starting material is incorporated into the product

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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Synthesis. Design a synthetic route to perform the transformations shown below. You may use any other reagents necessary, as long as the starting material is incorporated into the product

### Short Synthesis Process

The image depicts a chemical reaction sequence labelled as a short synthesis.

- **First Molecule (Reactant)**:
  - This molecule is a carboxylic acid (with a -COOH group). The structure is partially specified by the presence of hydroxyl groups (-OH) and a carboxyl group (-COH).
  - The molecular structure can be broken down as follows:
    - Starting from the left, the molecule has a hydroxyl group (OH) attached to a carbon atom.
    - This carbon is connected to another carbon atom, which has another hydroxyl group attached.
    - The next carbon atom is bonded with a carbonyl group (C=O) and a hydroxyl group.

- **Arrow**:
  - An arrow pointing to the right indicates a chemical reaction or transformation leading from the reactant to the product.

- **Second Molecule (Product)**:
  - After the transformation, the molecular structure slightly changes.
  - The fundamental structure remains the same, with a hydroxyl group, another hydroxyl group on the second carbon, and a carboxyl group at one end.
  - It seems to be the same molecule represented in another possible conformation, showcasing the same chemical groups (hydroxyl, carbonyl, and hydroxyl).

This diagram effectively depicts a simple step in organic synthesis, demonstrating how a molecule can undergo slight structural reconfiguration while maintaining its functional groups, which are crucial in defining its chemical behavior and potential reactions.

### Key Concepts:
- **Hydroxyl Group (-OH)**: Consists of an oxygen atom bonded to a hydrogen atom. It is polar and makes the molecule hydrophilic (water-attracting).
- **Carbonyl Group (C=O)**: A functional group composed of a carbon atom double-bonded to an oxygen atom. Common in aldehydes and ketones.
- **Carboxyl Group (-COOH)**: Combination of a carbonyl and a hydroxyl group; common in carboxylic acids, contributing to acidity.
- **Stereochemistry**: The three-dimensional arrangement of atoms within the molecule, which can influence its reactivity and interaction with other molecules.

Understanding these fundamental structures and transformations is pivotal in fields such as organic chemistry, biochemistry, and pharmaceuticals, where synthesis routes and compound modification are critical.
Transcribed Image Text:### Short Synthesis Process The image depicts a chemical reaction sequence labelled as a short synthesis. - **First Molecule (Reactant)**: - This molecule is a carboxylic acid (with a -COOH group). The structure is partially specified by the presence of hydroxyl groups (-OH) and a carboxyl group (-COH). - The molecular structure can be broken down as follows: - Starting from the left, the molecule has a hydroxyl group (OH) attached to a carbon atom. - This carbon is connected to another carbon atom, which has another hydroxyl group attached. - The next carbon atom is bonded with a carbonyl group (C=O) and a hydroxyl group. - **Arrow**: - An arrow pointing to the right indicates a chemical reaction or transformation leading from the reactant to the product. - **Second Molecule (Product)**: - After the transformation, the molecular structure slightly changes. - The fundamental structure remains the same, with a hydroxyl group, another hydroxyl group on the second carbon, and a carboxyl group at one end. - It seems to be the same molecule represented in another possible conformation, showcasing the same chemical groups (hydroxyl, carbonyl, and hydroxyl). This diagram effectively depicts a simple step in organic synthesis, demonstrating how a molecule can undergo slight structural reconfiguration while maintaining its functional groups, which are crucial in defining its chemical behavior and potential reactions. ### Key Concepts: - **Hydroxyl Group (-OH)**: Consists of an oxygen atom bonded to a hydrogen atom. It is polar and makes the molecule hydrophilic (water-attracting). - **Carbonyl Group (C=O)**: A functional group composed of a carbon atom double-bonded to an oxygen atom. Common in aldehydes and ketones. - **Carboxyl Group (-COOH)**: Combination of a carbonyl and a hydroxyl group; common in carboxylic acids, contributing to acidity. - **Stereochemistry**: The three-dimensional arrangement of atoms within the molecule, which can influence its reactivity and interaction with other molecules. Understanding these fundamental structures and transformations is pivotal in fields such as organic chemistry, biochemistry, and pharmaceuticals, where synthesis routes and compound modification are critical.
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