Synthesis of Heilonine (1)ª Please explain the mechanism of the transition metal catalyzed [2+2 + 2] cycloisomerization reaction shown in the image. I need a curved arrow mechanism shown as well as a verbal description of the mechanism. Synthesis of Heilonine (1) a Me 25 N H Me ཀ+ b. RhCI(PPh3)3 (cat.) Me Me EtOH, 80 °C H yield 89% yield Me- Me 27 Me- 28 Me c. L י

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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
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Synthesis of Heilonine (1)ª Please explain the
mechanism of the transition metal catalyzed
[2+2 + 2] cycloisomerization reaction shown in
the image. I need a curved arrow mechanism shown
as well as a verbal description of the mechanism.
Synthesis of Heilonine (1) a
Me
25
N
H
Me
ཀ+
b. RhCI(PPh3)3 (cat.)
Me
Me
EtOH, 80 °C
H
yield
89% yield
Me-
Me
27
Me-
28
Me
c. L
י
Transcribed Image Text:Synthesis of Heilonine (1)ª Please explain the mechanism of the transition metal catalyzed [2+2 + 2] cycloisomerization reaction shown in the image. I need a curved arrow mechanism shown as well as a verbal description of the mechanism. Synthesis of Heilonine (1) a Me 25 N H Me ཀ+ b. RhCI(PPh3)3 (cat.) Me Me EtOH, 80 °C H yield 89% yield Me- Me 27 Me- 28 Me c. L י
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