sj Predict Products. Using line structures, give the major product of each reaction below. DON'T SHOW MECHANISMS HERE. Use scratch paper if needed. NR if no reaction; indicate stereochemistry as we have discussed (E=enantiomer; D = Diastereomer) 1 HBr HCI a Br2 HO- h b H2SO4 Br ONa H2SO4 H20 Br H2 j Но Pd/C CI 1. O3 LDA k e THF, A 2. H2О2 1. O3 NACN 2. Me2s DMSO
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
![s] Predict Products. Using line structures, give the major product of each reaction
below. DON'T SHOW MECHANISMS HERE. Use scratch paper if needed. NR if no reaction;
indicate stereochemistry as we have discussed (E=enantiomer; D = Diastereomer)
1
HBr
HCI
a
Br2
OH
b
HO,
H2SO4
Br
ONa
H2SO4
HO,
H20
Br
H2
OH
d
Pd/C
1. O3
LDA
THF, A
2. H2O2
1. O3
NACN
2. Me,s
DMSO](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F350fe5bd-aa77-4649-b0ff-004ebcdeb53d%2F7eb5e07a-a016-4f32-babb-4cc986b071e2%2F2s7qg5_processed.jpeg&w=3840&q=75)
Step by step
Solved in 3 steps with 2 images
