Suppose that you wanted to study retroviral integration mechanisms by determining the nucleotide sequence at the integration site-sev- eral dozen nucleotides on each side of the viral-cellular DNA junc- tion. Describe how to isolate DNA containing a junction site in amounts sufficient for sequence analysis.

Suppose that you wanted to study retroviral integration mechanisms by determining the nucleotide sequence at the integration site-sev- eral dozen nucleotides on each side of the viral-cellular DNA junc- tion. Describe how to isolate DNA containing a junction site in amounts sufficient for sequence analysis.

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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