Sultanilamide is an antimicrobial drug that mimics the shape of an important substrate for a particular bacterial enzyme, thereby inhibiting the enzyme by binding at the active site. This type of inhibition is known as O 1) noncompetitive inhibition. 2) feedback inhibition. 3) pharmacological inhibition 4) allosteric inhibition. O 5) competitive inhibition.

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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**Enzyme Inhibition: Competitive Inhibition**

**Question:**
Sulfanilamide is an antimicrobial drug that mimics the shape of an important substrate for a particular bacterial enzyme, thereby inhibiting the enzyme by binding at the active site. This type of inhibition is known as:

**Options:**
1. Noncompetitive inhibition.
2. Feedback inhibition.
3. Pharmacological inhibition.
4. Allosteric inhibition.
5. Competitive inhibition.

**Explanation:**
In competitive inhibition, a substance mimics the substrate and competes for binding at the enzyme’s active site. This results in enzyme inhibition since the true substrate cannot bind and the reaction does not proceed as usual. In this scenario, Sulfanilamide acts as a competitive inhibitor by mimicking the substrate’s shape and binding to the active site of the enzyme, preventing the normal substrate from binding.

Correct Choice: **5) Competitive inhibition**
Transcribed Image Text:**Enzyme Inhibition: Competitive Inhibition** **Question:** Sulfanilamide is an antimicrobial drug that mimics the shape of an important substrate for a particular bacterial enzyme, thereby inhibiting the enzyme by binding at the active site. This type of inhibition is known as: **Options:** 1. Noncompetitive inhibition. 2. Feedback inhibition. 3. Pharmacological inhibition. 4. Allosteric inhibition. 5. Competitive inhibition. **Explanation:** In competitive inhibition, a substance mimics the substrate and competes for binding at the enzyme’s active site. This results in enzyme inhibition since the true substrate cannot bind and the reaction does not proceed as usual. In this scenario, Sulfanilamide acts as a competitive inhibitor by mimicking the substrate’s shape and binding to the active site of the enzyme, preventing the normal substrate from binding. Correct Choice: **5) Competitive inhibition**
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