STION 21 e studying two proteins that you suspect cap the ends of actin filaments. To detemmine if
STION 21 e studying two proteins that you suspect cap the ends of actin filaments. To detemmine if
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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
Transcribed Image Text:QUESTION 21
You are studying two proteins that you suspect cap the ends of actin filaments. To detemine if they do and to determine which end they cap, you measure filament formation as a function of actin concentration in the absence of either protein, in the presence of protein 1 and in the presence
of protein 2 (each individually). You get the results below. Which protein caps the plus end and which caps the minus end?
(A) NO ADDED PROTEIN
(B) PROTEIN 1
(C) PROTEIN 2
filament
monomer
filament
monomer
filament
monomer
0.2
0.4
0.6
0.8
0.2
0.4
0.6
0.8
0.2
0.4
0.6
0.8
actin (uM)
actin (µM)
actin (µM)
O Neither protein caps either end of actin.
O Both proteins cap the plus end
O Protein 1 caps the minus end and protein 2 the plus end.
O Protein 2 caps the minus end and protein 1 the plus end
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